Oligest is a Dienogest 2 mg tablet, 28 tablets per box, manufactured by OLIC (Thailand). Dienogest is a 19-nortestosterone derivative that acts as a selective progesterone-receptor agonist, lowering endogenous estradiol and producing a sustained high-progestogen, moderately-low-estrogen state. This causes both eutopic and ectopic endometrial tissue to atrophy and become less inflamed, and it inhibits ovulation in most patients. Oligest contains the same active ingredient as Bayer's Visanne but is used specifically to treat endometriosis pain — it is not a contraceptive. It is intended for long-term, continuous use -- consult a doctor or pharmacist before use.

Dienogest 2 mg treats pain from endometriosis — a condition where tissue similar to the uterine lining grows outside the uterus, such as on the ovaries, fallopian tubes, or peritoneum, forming ovarian chocolate cysts. It causes chronic pelvic pain, severe period pain, and pain during intercourse. Oligest reduces inflammation of this misplaced tissue, easing pain, though some patients may still need surgery as well. It is intended for patients diagnosed with endometriosis or an endometriosis-related ovarian cyst, not for general period pain unrelated to endometriosis. Some patients also experience infertility alongside these symptoms.

Take one Oligest tablet daily, continuously, with no pill-free break — unlike contraceptive pills that have a 7-day gap. Start the next pack the day after the last tablet of the previous one. You may start on any day of the menstrual cycle, and it can be taken with or without food. Take it at the same time each day to keep drug levels steady. If you miss a dose, take it as soon as you remember, then resume your usual time the next day. Vomiting or diarrhoea within 3-4 hours of taking a tablet counts as a missed dose — take another tablet. Any other hormonal contraceptive must be stopped before starting Oligest.

Common side effects from the UK SmPC (N=290): headache 9.0%, breast discomfort 5.4%, depressed mood 5.1%, and acne 5.1%. Other reported effects include insomnia, irritability, reduced libido, migraine, abdominal pain, bloating, diarrhoea or vomiting, hair loss, back pain, and fatigue. Canada's product monograph (N=303), a different pooled dataset, reports slightly different rates: headache 6.6%, breast discomfort 5.3%, weight gain 3.6%, nausea 3.6%, depressed mood 3.0%, and ovarian cyst 2.6%. Anyone with a history of depression should be monitored and should stop the medicine and consult a doctor or pharmacist immediately if symptoms worsen. Stop taking Oligest and see a doctor immediately for: one-sided leg swelling and pain, sudden chest pain, sudden breathlessness, one-sided numbness or weakness, a new or worsening migraine, acute liver dysfunction such as yellowing of the skin or eyes, or heavy vaginal bleeding causing anaemia.

Oligest is not a contraceptive. Although it suppresses ovulation in most patients, its contraceptive efficacy has never been tested. Anyone needing contraception must use a non-hormonal method (such as condoms), and any other hormonal contraceptive, such as Cerazette, must be stopped before starting Oligest. Pregnancy should be excluded before starting. Do not use during pregnancy or while breastfeeding, or if you currently have a venous blood clot, or have current or past arterial/cardiovascular disease -- such as angina, stroke, or a transient ischaemic attack (TIA) -- diabetes with vascular complications, severe liver disease (current or past, until liver values normalise), a liver tumour whether benign or malignant, a known or suspected sex-hormone-dependent cancer, undiagnosed vaginal bleeding, or known hypersensitivity to dienogest or any of its excipients. In adolescents aged 12 to under 18 using it for 12 months, average lumbar spine bone density dropped by 1.2%, trending back toward baseline 6 months after stopping — it is not recommended before a first period. In adults using it for 6 months, no significant bone density loss has been found.

Some medicines lower Dienogest blood levels, including rifampicin (by up to 83%), carbamazepine, phenytoin, phenobarbital, topiramate, griseofulvin, and St John's wort, which may reduce its effectiveness. Others raise Dienogest levels, including ketoconazole (almost 3-fold), itraconazole, erythromycin, clarithromycin, verapamil, diltiazem, and grapefruit juice. If you take any other medicines regularly, including any other medicines you take on your own or herbal products, tell your pharmacist before starting Oligest. That includes pain relievers you buy for yourself, such as Tylenol.

Treatment response is typically assessed at around 3 months, the point at which studies found 37.3% of patients had at least a 50% reduction in pain without extra pain medication, compared with 19.8% on placebo. If it is working, it can be continued; no source states a fixed maximum duration, and continuous use of 15 months or longer has been studied. If there is no improvement, see a doctor to consider other options. The irregular bleeding common in the early months usually improves the longer treatment continues. Discontinuation due to bleeding is under 1%, and stopping around menopause should be considered.

Where to buy Oligest (Dienogest 2 mg)?

Order online from Intimo Life for nationwide delivery in Thailand within 1-3 business days. Packaging is discreet and does not display the product name on the outside.