Cialis (Tadalafil) — A performance enhancer for men that stands out with its long-lasting effect of up to 36 hours, providing confidence and flexibility in daily life.
⏰ Lasts up to 36 hours — No need to rush planning, live life relaxed and naturally
💪 High flexibility — Ready to use throughout the medication's active period, not limited to just once
🍽️ Not affected by food — Can be taken with meals without reducing effectiveness
💊 Available in 2 strengths — Cialis 20mg for on-demand use and Cialis 5mg for daily use
🌟 High-quality Tadalafil ingredient — Medically certified, safe and effective
🎯 Perfect for modern lifestyle — For men who want confidence and convenience in self-care
Erectile dysfunction medication is a medically proven option for men experiencing sexual performance issues (Erectile Dysfunction). Cialis is a PDE-5 Inhibitor containing Tadalafil 20 mg, manufactured by Eli Lilly. Known as "The Weekend Pill" due to its 36-hour duration — significantly longer than Kamagra Oral Jelly and Talafil.
📊 Key Statistics
Erectile Dysfunction (ED) — Affects over 40% of Thai men by age 40, with prevalence increasing with age
Tadalafil lasts up to 36 hours — the longest-acting PDE-5 Inhibitor, eliminating the need to time intimacy precisely
Cialis can be taken with food without reduced effectiveness, unlike Sildenafil which works best on an empty stomach
See other ED treatments in the ED Treatment collection
🏭 Cialis is manufactured by Eli Lilly, a world-leading pharmaceutical company. It is the originator brand for Tadalafil, approved by the US FDA and Thai FDA — the gold standard in ED treatment.
⚠️ Cialis requires sexual stimulation to work — it does not cause an automatic erection.
Medically reviewed by
ทีมเนื้อหา Intimo Life | แหล่งข้อมูล: NHS, StatPearls, Drugs.com
Last reviewed: 2026-02-17
About Cialis
What is Cialis?
Cialis is an oral erectile dysfunction medication containing Tadalafil 20 mg as its active ingredient. It belongs to the PDE-5 Inhibitor drug class and is manufactured by Eli Lilly, a global pharmaceutical leader.
Tadalafil works by inhibiting the PDE-5 enzyme, increasing cGMP levels in the smooth muscle of penile blood vessels. This causes vasodilation, allowing increased blood flow to the penis and enabling an erection when sexually stimulated.
Cialis is distinguished by its 36-hour duration of action, earning it the nickname "The Weekend Pill." This eliminates the need to precisely time the medication. Additionally, it can be taken with food without affecting efficacy.
Cialis contains the same active ingredient as Talafil (a more affordable Thai generic), differing only in brand name and price.
What is Cialis used for?
Erectile Dysfunction (ED): Cialis treats the inability to achieve or maintain an erection sufficient for sexual intercourse. Used as-needed at 10–20 mg doses.
Benign Prostatic Hyperplasia (BPH): Tadalafil 5 mg taken daily is approved for treating urinary symptoms from an enlarged prostate, and can treat both ED and BPH simultaneously.
Not for: Women, children, or those without ED. Cialis is not an aphrodisiac and does not increase penis size.
Important: Sexual stimulation is required for the medication to work. Cialis does not cause an automatic erection.
How to Take Cialis / Dosage
As-needed use:
Starting dose: 10 mg at least 30 minutes before sexual activity
Can be adjusted to 20 mg or reduced to 5 mg based on response
Do not take more than once in 24 hours
Effective for up to 36 hours
Daily use:
2.5–5 mg once daily at the same time each day
Suitable for those with sexual activity more than twice per week
Appropriate for men with concurrent BPH
Advantage: Can be taken with or without food — high-fat meals do not affect absorption.
Important:
Never combine with any nitrate medications (e.g., sublingual Isosorbide)
Limit alcohol consumption as it may increase side effects
If an erection lasts more than 4 hours (priapism), seek medical attention immediately
Side Effects of Cialis
Common side effects:
Headache
Indigestion / heartburn
Back pain / muscle aches (typically 12–24 hours after dosing)
Flushing
Nasal congestion / runny nose
Serious side effects (rare, but seek immediate medical attention):
Priapism — erection lasting more than 4 hours, may cause permanent tissue damage
Sudden vision loss (NAION) — very rare; stop the medication and see an ophthalmologist immediately
Sudden hearing loss — may be accompanied by tinnitus; stop immediately
Severe drop in blood pressure — especially when combined with antihypertensives
Key note: Back pain and muscle aches are more specific to Tadalafil than Sildenafil, typically occurring 12–24 hours after dosing.
Contraindications & Precautions
Do not use:
Nitrate medications of any kind (Nitroglycerin, Isosorbide dinitrate/mononitrate) — may cause life-threatening hypotension
Allergy to Tadalafil or any component of the medication
Heart attack or stroke within the past 90 days
Low blood pressure (below 90/50 mmHg)
Uncontrolled high blood pressure (above 170/100 mmHg)
Use with caution:
Alpha-blockers (e.g., Doxazosin) — must be stabilised before starting Tadalafil
Severe liver or kidney impairment — dose reduction may be needed
Conditions affecting erection, such as Peyronie's disease
Do not combine with other PDE-5 Inhibitors
How Does Cialis Compare to Other ED Medications?
Cialis vs. Viagra (Sildenafil): Both are PDE-5 Inhibitors, but Cialis lasts significantly longer (36 hrs vs. 4–6 hrs) and can be taken with food. Viagra has a slightly faster onset (30 min vs. 30–60 min).
Cialis vs. Kamagra Oral Jelly: Kamagra contains Sildenafil 100 mg in a gel form for rapid absorption, lasting 4–6 hours. Cialis offers a longer duration and greater flexibility with timing.
Cialis vs. Talafil: Same active ingredient — Tadalafil. Cialis is the originator brand by Eli Lilly at a higher price. Talafil is a Thai generic with equivalent efficacy at a more accessible price.
How Long Does Cialis Last?
Cialis begins working within 30 minutes to 2 hours after ingestion (most commonly within 1 hour) and remains effective for up to 36 hours.
Action timeline:
30 min – 2 hrs: Medication becomes active; can respond to sexual stimulation
2–6 hrs: Peak effectiveness window
6–36 hrs: Still effective, though potency gradually decreases
Daily use (2.5–5 mg): After 4–5 days of continuous use, steady-state blood levels are achieved, providing round-the-clock readiness without advance planning.
Factors affecting response: Age, overall health, concomitant medications, and severity of ED.
Where Can I Buy Cialis?
Cialis is a pharmacist-dispensed medication. You can order online from Intimo Life.
Can I buy Cialis online?
Yes. Order through Intimo Life — select the product, consult with a licensed pharmacist online, and receive your medication at home.
Do I need a prescription?
A doctor's prescription is not required, but the medication must be dispensed by a licensed pharmacist. At Intimo Life, our pharmacist will review your symptoms and health history to confirm suitability before shipping.
How does Intimo Life ship orders?
We deliver nationwide in Thailand with discreet packaging — no product names on the outside.
Both contain the same active ingredient — Tadalafil. Cialis is the originator brand by Eli Lilly at a higher price. Talafil is a Thai generic at a significantly lower cost with equivalent efficacy — ideal for those seeking a more affordable option.
Yes. This is an advantage of Tadalafil over Sildenafil (Viagra) — food, including high-fat meals, does not affect Tadalafil absorption. No need to worry about meal timing.
Cialis lasts up to 36 hours — significantly longer than Viagra (4–6 hrs). This is why it's called "The Weekend Pill" — you can take it on Friday and it remains effective through Sunday, eliminating time pressure around intimacy.
It's recommended to limit alcohol consumption with Cialis. Small amounts may not have a significant effect, but excessive drinking can cause blood pressure drops, dizziness, and reduce the medication's effectiveness.
As-needed: 10–20 mg taken 30 minutes before sexual activity, effective for 36 hours — suitable for infrequent use. Daily: 2.5–5 mg taken every day for round-the-clock readiness — ideal for frequent activity or concurrent BPH symptoms.
Both Tadalafil and nitrates dilate blood vessels and lower blood pressure. Used together, they potentiate each other's effects, potentially causing severe hypotension, shock, unconsciousness, or death. Never combine them — this includes sublingual tablets, nitrate sprays, and poppers.
Related Products
Products with the same active ingredient or treating the similar condition.