Tadarise-5

Tadarise-5 is a yellow film-coated tablet holding 5 mg of tadalafil per tablet, made by Sunrise Remedies in India. A box holds 10 strips of 10 tablets, and the box says the yellow colour comes from tartrazine.

Tadalafil 5mg belongs to the PDE5 inhibitor group (it blocks phosphodiesterase type 5) and was approved by the US FDA in 2003. It stops the breakdown of cGMP, so smooth muscle in the penis, the prostate and the lung vessels stays relaxed for longer. Sexual stimulation is still needed for it to work.

This page follows documents for tadalafil in general: the Cialis label, the NHS and MedlinePlus. No Sunrise Remedies page or Tadarise-5 leaflet could be found, so read the leaflet in the box too.

Tadalafil 5mg taken once a day is used in two main cases, going by documents for tadalafil in general.

• Erectile dysfunction (ED) — helps an erection happen when there is sexual stimulation.
• Urinary symptoms from an enlarged prostate (BPH), including ED and BPH together.

In the Cialis label's BPH studies of 5 mg once daily, the urinary symptom score (IPSS) at week 12 fell by 4.8 against 2.2 on placebo (Study J) and by 5.6 against 3.6 (Study K). The EMA says 5 mg once daily suits men who expect to use it often, about twice a week or more, and that the need for daily use should be reviewed regularly.

Tadalafil is also used for pulmonary arterial hypertension, but that is a different, higher-dose product and not the purpose of this 5 mg tablet.

A doctor or pharmacist sets the dose. General information for tadalafil 5 mg taken once a day:

• Time — 1 tablet a day at the same time each day, whenever sex happens.
• Food — with or without food; food does not change absorption much.
• Swallowing — whole, with water. Do not split the tablet.
• Never more than one a day — do not take more than 1 tablet in a day.
• Missed dose — take it when you remember unless the next one is nearly due. Never double up.
• Strip or box — 1 strip of 10 tablets lasts 10 days and 1 box of 100 tablets lasts 100 days. If you are new to daily use, starting with a strip lets you see how it suits you before you pick a box for continued use.

From tadalafil references (Cialis label, NHS, MedlinePlus).

• Common — headache, indigestion, muscle aches, back pain, a stuffy nose, a flushed face and dizziness.
• Figures from 5 mg once-daily trials (581 men against 576 on placebo) — headache 4.1% against 2.3%, indigestion 2.4% against 0.2%, back pain 2.4% against 1.4%, muscle pain 1.2% against 0.3%.
• Blood pressure — falls by about 7 mm Hg systolic and 5 mm Hg diastolic, for up to 12 hours.

Stop and get help quickly for an erection lasting more than 4 hours, sudden loss of vision or hearing (it may be permanent), an allergic reaction, trouble breathing, palpitations or a seizure. If you have chest pain during sex, call emergency services.

• Nitrates — never use tadalafil 5mg with any nitrate, such as GTN for chest pain.
• Riociguat and other guanylate cyclase stimulators — do not combine.
• Serious allergy to tadalafil — do not use.
• Heart disease — not recommended after a heart attack within 90 days, with unstable angina, after a stroke within 6 months, or where a doctor judges sex inadvisable.
• Blood pressure — low blood pressure, or high blood pressure that is not controlled.
• Ask before use — liver or kidney problems, leukaemia, multiple myeloma, sickle cell anaemia, past vision loss in one eye from reduced optic nerve blood flow, or a curved or bent penis.
• Groups to avoid — pregnancy, breastfeeding and children. Do not combine with other PDE5 inhibitors.
• Recreational drugs — poppers and illegal drugs raise the risk.

• Talafil (Tadalafil) — a long-acting tadalafil brand in 5, 10 and 20 mg. Pick it when you want a strength other than 5 mg.
• Cialis (Tadalafil) — the original brand, in 5 mg and 20 mg. Pick it when you want the original brand.
• Apcalis SX 20 (Tadalafil) — a 20 mg oral jelly, not a tablet. Pick it when you want a jelly form.
• Kamagra 100 Gold (Sildenafil) — 100 mg, shorter acting than tadalafil. Pick it when you want to take it only as needed.

In short: Tadarise-5 suits taking 5 mg once a day, continuously. For another strength or the original brand look at Talafil or Cialis, for a jelly look at Apcalis SX 20, and for a shorter-acting option look at Kamagra 100 Gold. If you are unsure which suits you, ask a pharmacist first.

• Nitrates — never combine.
• Alpha blockers such as tamsulosin, doxazosin and alfuzosin — blood pressure can drop; for BPH the combination is not recommended.
• CYP3A4 inhibitors such as ketoconazole and ritonavir — the once-daily maximum is 2.5 mg.
• Others — itraconazole, clarithromycin, erythromycin, rifampin, HIV protease inhibitors, antiepileptics and blood pressure medicines.
• Grapefruit — avoid grapefruit juice while taking tadalafil (NHS).
• Alcohol — heavy drinking (5 units or more) can cause dizziness on standing, and it makes erections harder.
• St. John's wort — tell a pharmacist or doctor.

Tell a pharmacist or doctor about every medicine and supplement you take.

The information for tadalafil differs by how it is taken.

• 5 mg once a day — meant to hold a steady level, not to be timed around sex. The half-life is about 17.5 hours, the blood level settles within 5 days of daily use, and it is about 1.6 times that of a single dose.
• Peak level — about 2 hours after one tablet.
• On-demand use (not 5 mg every day) — the NHS says to take it about 30 minutes before sex, and the effect can last up to 36 hours.

For BPH symptoms, the Cialis label's studies measured 5 mg once daily at week 12. How soon you notice a change differs from person to person. If you see no change after taking it, ask a pharmacist or doctor.

Where can you buy Tadarise-5?

Order online from Intimo Life, shipped across Thailand in 1-3 working days. Packed discreetly for privacy, with no product name on the parcel.