Rosuvastatin calcium
Crestor
Crestor — an original AstraZeneca statin with Rosuvastatin calcium, flexible to take any time of day
💊 Active ingredient: Rosuvastatin calcium
⏱️ How to use: take 1 tablet daily, same time each day
🍽️ Conditions: can be taken with or without food
📦 Pack: box of 2 strips, 28 tablets — available in 10mg and 20mg
⚡ Highlight: original AstraZeneca brand, strong LDL reduction
🌡️ Storage: below 30°C, away from sunlight
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Shipping
Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.
What is Crestor?
Crestor is a statin (rosuvastatin calcium 20mg) made by AstraZeneca that lowers blood cholesterol. It works by blocking HMG-CoA reductase, an enzyme the liver uses to make cholesterol, which reduces LDL cholesterol and raises HDL cholesterol. It suits people with high cholesterol who need long-term cardiovascular risk control under a doctor's ongoing supervision with regular blood tests.
🛒 Box of 2 strips, 28 tablets · Genuine AstraZeneca original · Fast delivery from Intimo Life — use under a doctor's ongoing care throughout treatment.
Product Description
Statin-class cholesterol medicine Crestor, with rosuvastatin calcium 20mg, is made by AstraZeneca. It works by blocking HMG-CoA reductase in the liver, reducing cholesterol production and helping clear LDL from the bloodstream. It suits people with high blood cholesterol who need long-term management, especially those at higher cardiovascular risk.
📊 Notable facts
- The VOYAGER meta-analysis found rosuvastatin 20mg lowers LDL cholesterol by an average of about 50%
- Rosuvastatin's half-life runs about 19 hours, so it works equally well any time of day, unlike Bestatin (Simvastatin), which is recommended at bedtime
- Rosuvastatin is mainly processed through the CYP2C9 enzyme rather than CYP3A4, giving it fewer interaction risks than some other statins
🏭 Made by AstraZeneca, imported and distributed legally
⚠️ This is a long-term cholesterol medicine — use it continuously and get regular blood tests as your doctor advises
About Crestor
What is Crestor?
Crestor is a statin-class cholesterol medicine, the original AstraZeneca brand of rosuvastatin calcium. It works by blocking HMG-CoA reductase, the enzyme the liver relies on to make cholesterol. As the liver makes less cholesterol, it pulls more LDL ('bad' cholesterol) out of the bloodstream, lowering LDL levels while modestly raising HDL ('good' cholesterol). Rosuvastatin is one of the more potent statins available, often achieving a bigger LDL reduction at a lower dose than older statins such as simvastatin.
What is Crestor used for?
Crestor lowers total cholesterol and LDL cholesterol, reduces triglycerides, and raises HDL in people with dyslipidemia or high cholesterol. It suits those who have not reached their cholesterol targets through diet and exercise alone, or who carry a higher risk of cardiovascular disease — for example with diabetes, high blood pressure, or a prior history of narrowed coronary arteries. Doctors typically use Crestor as part of a long-term cardiovascular risk-management plan, not as a short course to stop as soon as cholesterol looks better.
How to take Crestor / Dosage
This Crestor box contains rosuvastatin calcium 20mg, taken as 1 tablet daily, swallowed whole with water. Pick a time that's easy to remember and stick with it every day. It can be taken before or after food, and — unlike some other statins — does not need to be taken at bedtime, since rosuvastatin's near-19-hour half-life keeps it working around the clock whether taken morning or evening. Your doctor sets the dose based on your starting cholesterol level and individual risk factors. Do not adjust the dose yourself, and do not stop taking it on your own even after your cholesterol numbers improve, since it's meant for continuous, long-term risk control.
Side effects of Crestor
Common Crestor side effects include headache, nausea, constipation, and mild muscle or joint aches, which are usually manageable and ease as the body adjusts. However, severe muscle pain, muscle weakness, or unusually dark urine call for stopping the medicine and seeing a doctor right away, as these can signal rhabdomyolysis (muscle breakdown) — rare but serious. Some people see a mild rise in liver enzymes or blood sugar while on a statin, which is why your doctor schedules periodic blood tests. Report any other unusual symptoms, such as a rash or facial swelling, to a doctor or pharmacist immediately as well.
Contraindications / Precautions
Crestor should not be used by anyone allergic to rosuvastatin or its ingredients, those with active liver disease of unexplained cause, or during pregnancy or breastfeeding, since the body needs cholesterol for fetal development. People with kidney disease, older adults, or those of East Asian descent may need a lower starting dose, as they carry a higher risk of muscle-related side effects. Tell your doctor about every condition and medicine you're currently taking before starting, and expect a liver function blood test before treatment begins and periodically afterward. Crestor should be used under a doctor's ongoing care throughout treatment, not started on your own without a confirmed cholesterol diagnosis.
Crestor vs other statin cholesterol medicines
Bestatin (Simvastatin) and Zimva (Simvastatin) are also statins, but simvastatin is less potent, usually needing a higher dose for the same LDL reduction, and works best taken at bedtime due to its short half-life. Crestor (rosuvastatin) is different — it's more potent at a lower dose, can be taken any time of day, and carries fewer interaction risks since it does not rely on the CYP3A4 enzyme like simvastatin does.
Simply put: for stronger action and flexible timing, choose Crestor; if your doctor started you on a lower dose or you're already used to bedtime dosing, Bestatin or Zimva are also valid statin options — the right choice always comes down to your doctor's advice.
Can Crestor be used with other medicines?
Crestor interacts with certain medicines worth watching for — especially cyclosporine (an immunosuppressant used after organ transplant), which significantly raises rosuvastatin blood levels, and gemfibrozil or other fibrate drugs, which raise the risk of muscle pain when combined. Anyone also taking warfarin may need more frequent INR (blood clotting) checks, since Crestor can enhance its effect. Antacids containing aluminum or magnesium can reduce Crestor absorption, so space doses at least 2 hours apart. Always tell your doctor or pharmacist about every medicine and supplement you're taking before starting anything new, so the risk can be assessed before it's prescribed.
How fast does Crestor work?
Crestor starts inhibiting cholesterol production in the liver within a few hours of the first dose, but a measurable drop in LDL cholesterol usually shows up on blood tests within the first 2 weeks, reaching a steady state around 4 weeks after starting or changing the dose. Doctors typically schedule a follow-up blood test 4-12 weeks after starting to check whether the current dose is working well enough. Don't expect to feel any difference right away — high cholesterol usually has no symptoms, so blood test results are the only reliable way to track progress.
Where to buy Crestor?
Where to buy Crestor?
Order online at Intimo Life for nationwide delivery across Thailand within 1-3 business days. Packaging is discreet and does not display the product name on the parcel.
⚠️ Disclaimer
The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.
References
- NHS UK. Rosuvastatin. NHS. 2024.
- MedlinePlus. Rosuvastatin. NIH. 2024.
- Sizar O, et al. Statin Medications. StatPearls, NCBI Bookshelf. 2024.
- Karlson BW, et al. Doses of rosuvastatin, atorvastatin and simvastatin that induce equal reductions in LDL-C (VOYAGER meta-analysis). PubMed. 2015.
- WebMD. Rosuvastatin Oral. WebMD. 2025.
Frequently Asked Questions
Crestor is the original AstraZeneca brand name for rosuvastatin calcium — the active ingredient is identical. Generic versions from other manufacturers, made after the patent expired, use the same rosuvastatin but under a different brand name.
Pricing varies by retailer and channel. Check the current price for the 28-tablet box in the product options at the top of this page.
If you remember the same day, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one — never double up, since it won't work faster and may raise side-effect risk. If you forget often, set a reminder or ask a pharmacist for tips.
If the muscle pain is mild and tolerable, keep monitoring it and mention it at your next doctor's visit. If the pain is severe, comes with noticeable weakness, or your urine turns unusually dark, stop the medicine and see a doctor immediately, as this can signal rare but serious muscle breakdown. Don't just stop on your own without telling your doctor — they may need to adjust the dose or switch you to a different medicine.
You should not stop on your own, even if your cholesterol test results improve, because Crestor manages long-term cardiovascular risk. Stopping on your own usually lets cholesterol levels rise back up within a few weeks, along with the associated heart disease risk. Always talk to your doctor first before adjusting or stopping the medicine.
Doctors typically check liver function before starting, then repeat a lipid panel around 4-12 weeks after starting or adjusting the dose to see whether it's working well enough. After that, follow-up tests are usually scheduled periodically at your doctor's discretion, with exact timing depending on your individual risk and health conditions.
Crestor should not be used during pregnancy or breastfeeding, since the body needs cholesterol for fetal development. If you're planning a pregnancy or are currently pregnant, tell your doctor right away so they can consider stopping the medicine or adjusting your cholesterol treatment plan.
Normal amounts of coffee or tea don't meaningfully interact with Crestor. As for grapefruit juice — unlike some statins, rosuvastatin isn't processed through the CYP3A4 enzyme grapefruit blocks, so its interaction risk is lower than simvastatin or atorvastatin. Still, mention regular large-volume grapefruit intake to your doctor.
Store Crestor at room temperature below 30°C, away from direct sunlight and moisture. Keep tablets in their original strip until you're ready to take them, close the box tightly, and keep it out of children's reach.
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