
Benzydamine Hydrochloride
Difflam Forte (Benzydamine Hydrochloride) Throat Spray 15ml
Difflam Forte — throat spray for sore throat and mouth ulcers. Benzydamine anti-inflammatory + analgesic.
💊 Active: Benzydamine HCl 3 mg/mL
⏱️ Use: 4-8 sprays/day every 1.5-3 hrs, spit out
🍽️ Condition: Any time, independent of meals
📦 Pack: 15 mL, Sugar Free
⚡ Highlight: Topical NSAID, fast relief
🌡️ Storage: Below 30°C, no direct sunlight
Shipping
Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.
Product Description
Difflam Forte throat spray contains Benzydamine Hydrochloride 3 mg/mL, a topical NSAID (non-steroidal anti-inflammatory drug) that acts locally on the mucous membranes of the mouth and throat to reduce inflammation and relieve pain — with minimal systemic absorption. Ideal for sore throat, throat irritation, mouth ulcers, and oral inflammation. Sugar-free formulation.
📊 Key facts about Difflam Forte:
- Benzydamine inhibits prostaglandin synthesis, directly reducing local tissue inflammation
- Topical analgesic effect within 30 minutes of application
- A 2022 BMC Primary Care Delphi consensus study confirmed Benzydamine's high effectiveness for acute sore throat
- Suitable for adults and children ≥6 years (different dose schedules)
- Indicated for sore throat from viral infection, post-surgical throat pain, mouth ulcers, and radiation mucositis
🏭 Manufactured by: Reckitt Benckiser Healthcare. Registration No. 1A 45/59
⚠️ If symptoms do not improve within 7 days, or if high fever develops, consult a doctor or pharmacist.
About Difflam Forte
What is Difflam Forte?
Difflam Forte is a throat spray containing Benzydamine Hydrochloride at 3 mg/mL — a higher concentration than standard Difflam (0.15%). It is a topical NSAID (non-steroidal anti-inflammatory drug) with a dual mechanism:
- Anti-inflammatory: Inhibits prostaglandin synthesis, reducing swelling and redness in the mucosal tissues of the mouth and throat
- Local analgesic: Reduces pain signal transmission in nerves at the site of application
Benzydamine Hydrochloride in Difflam Forte acts locally with minimal systemic absorption, resulting in fewer whole-body side effects compared to oral NSAIDs. The Sugar-free formulation is suitable for diabetic patients.
What conditions does Difflam Forte treat?
Difflam Forte is used to relieve symptoms arising from inflammation of the mouth and throat, including:
- Sore throat and throat irritation from viral or bacterial infections such as colds, flu, pharyngitis, or tonsillitis
- Mouth ulcers (aphthous ulcers) — relieves pain and burning, reduces inflammation around the ulcer
- Post-surgical sore throat following tracheal intubation — supported by meta-analysis evidence
- Oral mucositis from chemotherapy or radiotherapy — provides symptomatic relief during treatment
- Gingivitis and stomatitis — general oral mucosal irritation
Difflam Forte relieves symptoms and does not treat the underlying infection directly. If high fever or severe symptoms develop, consult a doctor or pharmacist.
How to use Difflam Forte / Dosage
How to use Difflam Forte throat spray:
- Shake the bottle gently before use
- Direct the spray nozzle towards the affected area in the mouth or throat
- Press 1-4 sprays per application, then spit out — do not swallow
Recommended Difflam Forte dosage:
- Adults and children ≥12 years: 4-8 sprays every 1.5-3 hours as needed
- Children 6-12 years: 1 spray per 4 kg body weight every 1.5-3 hours, maximum 4 sprays per application
- Children under 6 years: Not recommended — consult a doctor first
⚠️ Benzydamine should be used short-term (no more than 7 days). If symptoms do not improve, consult a doctor or pharmacist.
Side effects of Difflam Forte
Difflam Forte is generally well tolerated. Possible side effects include:
- Common: Numbness or mild tingling/stinging in the mouth and throat after spraying — a normal effect of Benzydamine that typically resolves within 5-10 minutes
- Uncommon: Dry mouth or mild nausea if larger amounts are swallowed
- Rare: Hypersensitivity reactions such as rash, facial swelling, or difficulty breathing — discontinue immediately and seek medical attention
- Photosensitivity: Rare reports of light sensitivity, particularly with prolonged use
As Benzydamine Hydrochloride has minimal systemic absorption when used topically, it does not cause the gastrointestinal side effects associated with oral NSAIDs.
Contraindications / Precautions
Contraindications for Difflam Forte:
- Known hypersensitivity to Benzydamine or any excipient in the formulation
- Children under 6 years of age (unless prescribed by a doctor)
Precautions:
- Pregnancy and breastfeeding: Consult a doctor or pharmacist before using Difflam Forte
- Aspirin or NSAID hypersensitivity: Cross-reactivity is possible
- Asthma patients: Use with caution — NSAIDs may trigger bronchoconstriction in susceptible individuals
- Do not swallow — for oral and throat use only
- Avoid use for more than 7 days without medical advice
⚠️ Use Difflam Forte as directed on the label or as advised by your pharmacist. When in doubt, always consult before use.
Difflam Forte vs other throat sprays
Comparison of throat sprays available at Intimo Life for sore throat and throat irritation:
- Difflam Forte (Benzydamine HCl) — Topical NSAID, reduces inflammation and relieves pain. Best for sore throat with inflammation, mouth ulcers, and post-surgical throat pain
- Propoliz Mouth Spray (Brazilian Green Propolis) — Natural herbal propolis extract, soothing for throat irritation, antioxidant properties. Best for mild throat irritation and those preferring natural products
- Nodogle Mouth Spray (Cetylpyridinium Chloride) — Antiseptic, kills oral bacteria. Best for bacterial throat irritation and bad breath prevention
Summary: Difflam Forte for real inflammation and throat pain (NSAID-backed) — Propoliz for mild irritation with a natural approach — Nodogle for antiseptic action and oral hygiene.
How quickly does Difflam Forte work?
Difflam Forte (Benzydamine) provides local analgesic relief within 30 minutes of spraying, with symptomatic relief typically lasting 3 hours. This is why it is recommended every 1.5-3 hours as needed.
- Anti-inflammatory effect: Noticeable within the first 1-2 hours
- Local pain relief: Within 30 minutes
- Duration of action: Approximately 2-3 hours per application
Difflam Forte acts faster than oral NSAIDs for oral conditions because the drug contacts the inflamed tissue directly, bypassing gastrointestinal absorption.
Can Difflam Forte be used with other medications?
Difflam Forte has minimal systemic absorption, resulting in very low interaction potential with other drugs. However, note the following:
- Oral NSAIDs (e.g. Ibuprofen, Naproxen, Aspirin): Avoid unnecessary concurrent use; although Benzydamine absorption is low, additive NSAID effects are theoretically possible
- Antacids/gastroprotective agents: No known interactions
- Antibiotics: No known interactions; can be used concurrently
- Mucolytics/expectorants: No known interactions
If you are taking multiple regular medications, always inform your doctor or pharmacist before starting Difflam Forte.
Where to buy Difflam Forte?
Where to buy Difflam Forte?
Order Difflam Forte online at Intimo Life. Nationwide delivery in Thailand within 1-3 business days. Discreet packaging — product name not shown on the outer box.
⚠️ Disclaimer
The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.
References
- NHS UK. Benzydamine: a non-steroidal anti-inflammatory drug (NSAID) to treat sore throats, mouth ulcers and teething. NHS. 2024.
- Passali D et al. International Delphi-based consensus on the appropriate use and effect of Benzydamine hydrochloride in the treatment of sore throat. BMC Primary Care. 2022.
- Kuriyama A, Aga M, Maeda H. Topical benzydamine hydrochloride for prevention of postoperative sore throat in adults undergoing tracheal intubation: a systematic review and meta-analysis. Anaesthesia. 2018.
- Farah B, Visintini S. Benzydamine for Acute Sore Throat: A Review of Clinical Effectiveness and Guidelines. CADTH. 2018.
Frequently Asked Questions
Difflam Forte can be used by children aged 6 years and older — 4 sprays per dose, every 1.5–3 hours, up to 4 times daily. For children under 6 years, safety data is insufficient, so consult a doctor or pharmacist before use.
Benzydamine Hydrochloride is the active ingredient in Difflam Forte — a topical NSAID that inhibits prostaglandin synthesis, reducing swelling, redness, and pain in the sprayed tissue. Minimal systemic absorption when used topically.
After spraying Difflam Forte, there is no need to spit it out — it works directly on the mucosal tissue in the throat and mouth. If a small amount naturally flows down the throat, this is not harmful. However, intentional swallowing in large amounts is not recommended. Avoid eating or drinking for at least 15–30 minutes after spraying to allow maximum effect.
Once opened, Difflam Forte should be used within 28 days (4 weeks). Store in a cool, dry place away from direct sunlight, below 30°C — refrigeration is not required. If the solution changes color or develops an unusual smell, discard immediately and do not use.
Pregnant or breastfeeding women should always consult a doctor or pharmacist before using Difflam Forte. Current data is limited — particularly in the first trimester and during breastfeeding. Although systemic absorption of Benzydamine through mucosa is low, a healthcare professional should assess safety on a case-by-case basis.
Difflam Forte contains a higher concentration of Benzydamine Hydrochloride (3 mg/mL) compared to standard Difflam (0.15% benzydamine). This provides stronger anti-inflammatory and analgesic action, making it more suitable for more severe symptoms such as significant throat inflammation or large mouth ulcers.
Difflam Forte is recommended for use no longer than 7 days. If sore throat or throat irritation does not improve within 7 days, or if high fever, enlarged lymph nodes, or worsening symptoms develop, consult a doctor or pharmacist for proper diagnosis and treatment.
Benzydamine in Difflam Forte suits adults and children ≥6 years with sore throat, throat irritation, or mouth ulcers. Sugar-free formula is suitable for diabetics. Those with aspirin or NSAID hypersensitivity should take caution; pregnant women should consult a doctor first.
Yes. Difflam Forte directly relieves the pain and burning of mouth ulcers (aphthous ulcers / canker sores), as Benzydamine reduces peri-ulcer inflammation and provides local pain relief. Spray 4-8 times directly onto the ulcer area, spit out, and repeat every 1.5-3 hours as needed.
Difflam Forte is priced at 299 THB for a 15 mL bottle at Intimo Life. Available to order online with nationwide delivery in Thailand within 1-3 business days.
Related Products
Products with the same active ingredient or treating the similar condition.
-
Betadine Gargle Antiseptic Mouthwash and Throat Gargle 30mlPovidone-iodine gargle: antiseptic sore throat relief
✓ In stock195.00 ฿ / -
Betadine Throat Spray 12mlPovidone-iodine throat spray for sore throat
✓ In stock189.00 ฿ /
Become a member of our store to receive news and exclusive discounts.







