Madonna One Emergency Contraceptive 1 Tablet (Levonorgestrel 1.5 mg)

Madonna One is a single-dose emergency contraceptive pill containing Levonorgestrel 1.5 mg, a synthetic progestin. Its primary mechanism is inhibiting or delaying ovulation — preventing the egg from meeting sperm. It may also thicken cervical mucus to impede sperm movement.

Manufactured by Biolab Co., Ltd., a Thai GMP-certified pharmaceutical company registered with the Thai FDA. The Madonna brand offers both a 1-tablet formulation (Madonna One) and a 2-tablet formulation, giving consumers options. The key advantage of Madonna One is a complete single-dose — no need to remember a second tablet 12 hours later.

Important: Madonna One is not an abortion pill. It does not terminate an established pregnancy and does not protect against sexually transmitted infections.

Madonna One is used to prevent pregnancy after unprotected sex or contraceptive failure, such as:

• Condom breakage or slippage during sex
• Missing 2 or more regular contraceptive pills in a row
• Having unprotected sex without any contraception
• Concern that your regular contraception may have failed

Take within 72 hours (3 days) after unprotected sex — the sooner, the more effective. Madonna One is not intended as regular contraception. If you have regular sexual activity, consult a pharmacist about suitable long-term contraception options.

How to take Madonna One emergency contraceptive:

• Take 1 tablet as soon as possible after unprotected sex
• Take within 72 hours (3 days) — earlier is more effective; do not wait for symptoms
• Can be taken with or without food; if you experience nausea, taking it with food or milk may help
• Single dose only — no need for a second tablet (unlike the 2-tablet Madonna formulation)

⚠️ If you vomit within 3 hours of taking Madonna One, take another tablet as the medication may not have been fully absorbed. Consult a pharmacist if you do not have a spare tablet.

Common side effects of Madonna One emergency contraceptive are usually mild and resolve within 1-2 days:

• Nausea / vomiting — most common; taking with food helps reduce this
• Lower abdominal pain — dull ache that typically resolves within 1-2 days
• Irregular spotting or your next period arriving earlier or later than usual
• Fatigue / headache — occurs but is not common
• Breast tenderness — mild, resolves within 1-2 days

Seek medical attention or consult a pharmacist if you experience:

• Severe abdominal pain (may indicate ectopic pregnancy risk)
• No period 3-4 weeks after taking — perform a pregnancy test

Madonna One does not cause infertility or have long-term effects on fertility.

Important precautions before taking Madonna One:

• Already pregnant — do not use. It will not terminate an existing pregnancy and is not an abortifacient
• Allergy to Levonorgestrel or any ingredient — consult a pharmacist first
• Certain medications (e.g., rifampicin, some anticonvulsants) may reduce Madonna One's effectiveness — inform your pharmacist of all medications you take
• Higher body weight — some studies suggest reduced efficacy at higher weight; ask a pharmacist about alternatives
• Breastfeeding — generally considered safe, but some guidelines suggest avoiding breastfeeding for 8 hours after taking to minimize infant exposure

Emergency contraceptive Levonorgestrel is not intended for regular use. Frequent use may disrupt menstrual cycles. Consult a pharmacist for suitable long-term contraception options.

Oral emergency contraceptives available at Intimo Life:

• Postinor (Levonorgestrel 0.75 mg) — 2-tablet regimen: take the first tablet immediately, the second 12 hours later. Price: ฿60. Good for those familiar with the classic regimen.
• Tansy One (Levonorgestrel 1.5 mg) — Single-dose, full-dose. Price: ฿80. Same active ingredient as Madonna One.
• Madonna One (Levonorgestrel 1.5 mg) — Single-dose, full-dose, manufactured by Biolab. Price: ฿55.

Quick guide: For simplicity, single dose, and best value — Madonna One at ฿55 is the most affordable option; for the same formula in another brand, choose Tansy One; for the classic 2-tablet regimen, choose Postinor.

Madonna One is absorbed quickly after ingestion, with peak blood levels typically reached within 1-2 hours. The active ingredient Levonorgestrel begins working to inhibit ovulation relatively soon after taking.

Key points to understand:

• Efficacy depends on timing relative to ovulation, not just speed of absorption. Taking Madonna One before or during the ovulatory window is more effective.
• The sooner you take it, the better — taking within 24 hours is more effective than 48-72 hours
• It has no effect on an already established pregnancy, so "how quickly it works" refers to preventing fertilization, not termination

Consult a pharmacist if you have questions about Levonorgestrel emergency contraception timing or effectiveness.

Where to buy Madonna One?

Order Madonna One emergency contraceptive online at Intimo Life. Shipping available throughout Thailand in 1-3 business days. All orders are packaged discreetly — no product name on the outer packaging.