Mamylase + Diastase + Aluminium Hydroxide + Scopolia Extract
Magesto-F Antacid and Digestive Enzyme Tablets 100s
Magesto-F — triple-layer antacid+enzyme tablet by Takeda. Relieves indigestion, bloating, gastric pain.
💊 Active: Mamylase+Diastase+Aluminium Hydroxide+Scopolia Extract
⏱️ Dosage: Adults 2–4 tablets, 3× daily after meals
🍽️ Condition: Take after meals
📦 Pack: 100 tablets, Takeda
⚡ Feature: Triple-layer separates enzymes from antacids
🌡️ Storage: Below 30°C, away from sunlight
Shipping
Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.
Product Description
Magesto-F is an antacid and digestive enzyme tablet by Takeda, built as a triple-layer (sandwich) tablet — outer layers contain antacids (Aluminium Hydroxide + Calcium Carbonate + Sodium Bicarbonate) while the middle layer holds digestive enzymes (Mamylase + Diastase) and Scopolia Extract. The sandwich design keeps enzymes away from the antacid environment, preserving full enzymatic activity.
📊 Digestive disorder statistics:
- Functional Dyspepsia affects 20–30% of the global population, accounting for 3–5% of all primary care visits
- Bloating, post-meal fullness, and belching affect 60–70% of dyspepsia patients
- Scopolia Extract provides anticholinergic antispasmodic action, reducing smooth muscle spasms that cause cramping
- The triple-layer (sandwich) design is unique to Magesto-F — digestive enzymes in the middle layer never contact the antacid outer layers before dissolution
🏭 Manufactured by Takeda Pharmaceutical, distributed in Thailand by Zuellig Pharma
⚠️ Consult a doctor or pharmacist if abdominal pain is severe or persistent
About Magesto-F
What is Magesto-F?
Magesto-F is an antacid and digestive enzyme combination tablet manufactured by Takeda Pharmaceutical, a leading Japanese pharmaceutical company. Its standout feature is the triple-layer (sandwich) tablet design that separates components into:
- Outer layers (Antacid): Aluminium Hydroxide 36.6 mg + Calcium Carbonate 200 mg + Sodium Bicarbonate 50 mg — neutralises stomach acid and relieves heartburn
- Middle layer (Enzyme): Mamylase 37.5 mg + Diastase 25 mg (digestive enzymes for starch/protein) + Scopolia Extract 2.5 mg (antispasmodic) + natural essential oils (cinnamon, clove, fennel, ginger) + Vitamin B1
The sandwich design prevents direct contact between enzymes and antacids, preserving full enzymatic activity — unlike single-layer combination tablets where antacid pH can degrade enzyme performance.
What does Magesto-F treat?
Magesto-F is indicated for gastric and digestive disorders including:
- 🍽️ Indigestion / Dyspepsia — bloating, fullness, and post-meal heaviness
- 🔥 Heartburn / Hyperacidity — neutralises excess stomach acid
- 💨 Bloating / Belching — relieves trapped gas in the digestive tract
- 😣 Gastric / Abdominal Pain and Cramping — Scopolia Extract relaxes smooth muscle spasms
- 🍺 Alcohol Hangover / Overeating
- 😤 Anorexia / Poor Appetite — natural essential oils stimulate digestive activity
- 🏥 Acute and Chronic Gastritis
- ⚙️ Gastric Hypomotility — supports gastric movement and motility
Magesto-F is suitable for acute symptomatic relief after meals. It is not a PPI and is not intended as long-term therapy for chronic acid reflux disease.
How to take Magesto-F / Dosage
Take Magesto-F as directed on the label or as advised by your doctor or pharmacist:
- Adults: 2–4 tablets, 3 times daily after meals
- Children 12–14 years: 1–3 tablets, 3 times daily after meals
- Children 7–11 years: 1–2 tablets, 3 times daily after meals
How to take: Swallow with water, or chew before swallowing. Always take after meals for best results.
Additional precautions:
- Do not exceed the stated dose
- Separate from certain antibiotics by at least 2 hours — aluminium/calcium may reduce antibiotic absorption
- Patients with kidney disease should use with caution due to aluminium accumulation risk
Magesto-F Side Effects
Magesto-F is generally well tolerated at recommended doses. Possible side effects include:
Anticholinergic effects (from Scopolia Extract):
- Dry mouth
- Blurred vision — due to anticholinergic activity of Scopolia Extract
- Palpitations, increased heart rate
- Urinary retention in some individuals
Antacid-related effects:
- Constipation or diarrhoea with prolonged use
- Nausea or vomiting in some cases
If unusual symptoms occur after taking Magesto-F, discontinue and consult a doctor or pharmacist.
Magesto-F Contraindications / Precautions
Magesto-F Contraindications:
- 🚫 Narrow-Angle Glaucoma — Scopolia Extract's anticholinergic action can raise intraocular pressure; strictly contraindicated
- 🚫 Known hypersensitivity to any component
- 🚫 Urinary retention — Scopolia may worsen the condition
Precautions:
- ⚠️ Pregnancy and breastfeeding — consult a doctor before using Magesto-F
- ⚠️ Children under 7 years — insufficient safety data
- ⚠️ Renal impairment — aluminium accumulation risk in kidney disease patients
- ⚠️ Drivers and machine operators — Scopolia-induced blurred vision may impair driving
- ⚠️ Concurrent antibiotic use — separate by at least 2 hours
Magesto-F vs Other Gastric Medications
Oral gastric medications available at Intimo Life for comparison:
- Magesto-F (Mamylase + Diastase + Aluminium Hydroxide + Scopolia) — antacid + digestive enzymes; fast onset; ideal for post-meal indigestion, bloating, and acute gastric discomfort
- Nexium (Esomeprazole) — PPI; reduces acid production at source; 24-hour duration; indicated for chronic GERD and peptic ulcers
- Omeprazole GPO (Omeprazole) — standard Thai PPI; cost-effective; suitable for long-term acid control
Summary: Magesto-F = antacid + digestive enzyme, fast relief for acute post-meal symptoms; Nexium and Omeprazole GPO = PPIs for long-term acid suppression in chronic reflux — different drug classes, choose based on your condition.
Can Magesto-F be used with other medications?
Magesto-F has clinically relevant interactions with certain medications:
- Fluoroquinolone and Tetracycline antibiotics — aluminium and calcium can chelate these antibiotics and reduce absorption; separate doses by at least 2 hours
- Other anticholinergic drugs — Scopolia Extract may potentiate anticholinergic effects (dry mouth, blurred vision, palpitations)
- Bisphosphonates (osteoporosis drugs) — separate from antacids by at least 30 minutes
- Levothyroxine — calcium may reduce absorption; separate by 4 hours
Inform your doctor or pharmacist of all medications you are taking before starting Magesto-F.
How fast does Magesto-F work?
Magesto-F acts rapidly through its multi-mechanism triple-layer design:
- Antacid action: Takes effect within 5–15 minutes — Aluminium Hydroxide + Calcium Carbonate + Sodium Bicarbonate directly neutralise gastric acid
- Digestive enzymes: Mamylase and Diastase become active in the small intestine, reducing bloating within 30–60 minutes
- Scopolia Extract (antispasmodic): Relieves abdominal cramping within 20–40 minutes
Overall, Magesto-F provides symptomatic relief within 15–30 minutes of ingestion. Duration of action is approximately 3–4 hours. Best suited for acute post-meal symptoms requiring prompt relief.
Where to buy Magesto-F?
Where to buy Magesto-F?
Order Magesto-F online at Intimo Life with nationwide delivery across Thailand in 1–3 business days. Discreet packaging — product name not shown on the parcel.
⚠️ Disclaimer
The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.
Frequently Asked Questions
Magesto-F is a triple-layer (sandwich) antacid and digestive enzyme tablet manufactured by Takeda Pharmaceutical. It combines digestive enzymes (Mamylase + Diastase), antacids (Aluminium Hydroxide + Calcium Carbonate + Sodium Bicarbonate), and Scopolia Extract for antispasmodic relief of indigestion, bloating, and gastric pain.
Magesto-F can be swallowed whole with water or chewed before swallowing — both methods are equally effective. Always take after meals for best results.
Magesto-F benefits include: relief of indigestion, bloating, fullness, belching, gastric pain, acute heartburn, symptoms from overeating or alcohol consumption, gastritis, and poor appetite — a multi-symptom digestive remedy in a single tablet.
Pregnant women should consult a doctor or pharmacist before using Magesto-F. Scopolia Extract has anticholinergic properties that may have implications during pregnancy. Always get medical advice before use.
Blurred vision after Magesto-F is a known anticholinergic side effect from Scopolia Extract and usually resolves when the drug wears off. However, if blurring is severe or accompanied by eye pain, stop the medication and consult a doctor immediately — especially if you have any risk of glaucoma.
Both Magesto-F and Combizym are digestive aids, but differ in formulation: Magesto-F combines digestive enzymes + antacids + Scopolia Extract, making it suitable for both indigestion and excess acid symptoms. Combizym focuses on multi-enzyme support (Pancreatin, Bromelain) for broader protein, fat, and carbohydrate digestion. Choose based on your primary symptoms.
If you miss a dose of Magesto-F, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double up doses to compensate for a missed one.
Magesto-F (100 tablets) is priced at 165 THB at Intimo Life — approximately 1.65 THB per tablet. It offers good value for those with frequent indigestion and bloating, as it combines digestive enzymes + antacid + antispasmodic in a single tablet.
Magesto-F has paediatric dosing: ages 7–11 years: 1–2 tablets; ages 12–14 years: 1–3 tablets, 3 times daily after meals. For children under 7 years, there is insufficient safety data — consult a doctor or pharmacist before use.
It is best to take Magesto-F with plain water after meals. Avoid taking it with coffee or tea — caffeine and tannins may reduce the effectiveness of the antacid component, and both coffee and tea stimulate gastric acid secretion, counteracting the purpose of the medication.
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