Omeprazole
Omeprazole GPO
Omeprazole GPO — A PPI acid reducer for treating acid reflux and stomach ulcers
💊 Active Ingredient: Omeprazole — Inhibits acid secretion for up to 24 hours
⏰ Take once daily, 30-60 minutes before breakfast. Swallow whole, do not crush or chew
📦 Packaged in a box of 10 strips, 10 capsules per strip (100 capsules total)
🏭 Manufactured by the Government Pharmaceutical Organization (GPO) — Thai standard, affordable price
🌡️ Store below 30°C, protect from light and moisture
Shipping
Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.
Product Description
Acid reflux medication is an important option for those with GERD, heartburn, and stomach ulcers. Omeprazole GPO is a Proton Pump Inhibitor (PPI) containing Omeprazole 20 mg, manufactured by GPO (Government Pharmaceutical Organization) of Thailand.
📊 Key Information
- GERD (Gastroesophageal Reflux Disease) is extremely common in Thailand, especially among those with high stress, spicy diets, or excess weight
- Omeprazole is the most widely used PPI in the world, highly effective at reducing stomach acid
- Omeprazole GPO is manufactured by Thailand's Government Pharmaceutical Organization — much cheaper than Nexium (Esomeprazole) with comparable efficacy
- See other digestive medications in the Digestive collection
🏭 Omeprazole GPO is manufactured by GPO (Government Pharmaceutical Organization). Thai FDA approved. It is a racemic mixture of Omeprazole, the same active ingredient used in originator brands worldwide.
⚠️ Do not use PPIs continuously for more than 8 weeks without medical consultation, as long-term use may have side effects.
About Omeprazole GPO
What is Omeprazole GPO?
Omeprazole GPO is a stomach acid reducer in the Proton Pump Inhibitor (PPI) class containing Omeprazole 20 mg, manufactured by the Government Pharmaceutical Organization (GPO) of Thailand.
Omeprazole works by irreversibly inhibiting the Proton Pump (H+/K+ ATPase) on stomach cell walls, reducing acid secretion by up to 90% with continuous use.
Omeprazole GPO is a racemic mixture (combination of R-isomer and S-isomer), unlike Nexium which contains only the S-isomer (Esomeprazole). However, clinical efficacy differs only slightly, and Omeprazole GPO is significantly cheaper.
What is Omeprazole GPO used for?
Key indications:
- GERD (Gastroesophageal Reflux Disease) — heartburn, acid regurgitation
- Gastric Ulcer
- Duodenal Ulcer
- Zollinger-Ellison Syndrome
- Combined with antibiotics for H. pylori eradication
- Prevention of NSAID-induced ulcers
Omeprazole GPO has the same indications as Nexium but is a racemic mixture at a much lower price — ideal for those requiring long-term use who want to save costs.
How to Take Omeprazole GPO / Dosage
Dosage: Take Omeprazole 20 mg once daily, 30 minutes before breakfast. Swallow the capsule whole with water — do not chew or crush.
Duration:
- GERD: 4–8 weeks
- Gastric ulcer: 4–8 weeks
- Duodenal ulcer: 2–4 weeks
- H. pylori eradication: 7–14 days (with antibiotics)
If you miss a dose: Take it as soon as you remember. If close to the next dose, skip it. Do not double the dose.
Important:
- Must be taken 30 minutes before food for optimal effect
- Do not use continuously for more than 8 weeks without medical advice
- If symptoms persist, see a doctor for further investigation
Side Effects of Omeprazole GPO
Common side effects:
- Headache
- Nausea, diarrhoea
- Abdominal pain, bloating
- Constipation
Long-term side effects (over 1 year):
- Hypomagnesemia (low magnesium)
- Vitamin B12 deficiency
- Increased fracture risk
- Increased risk of C. difficile infection
- Fundic Gland Polyps in the stomach (benign)
When to see a doctor:
- Vomiting blood or black stools
- Difficulty swallowing or unexplained weight loss
- Symptoms not improving after 2 weeks of use
Contraindications & Precautions
Do not use:
- Allergy to Omeprazole or other PPIs
- Do not use with Rilpivirine (HIV antiviral)
- Do not use with Nelfinavir
Use with caution:
- Ensure no gastric malignancy before starting — PPIs may mask symptoms
- Severe liver impairment — dose reduction may be needed
- Concurrent use with Clopidogrel — Omeprazole may reduce Clopidogrel efficacy
- Caution with Methotrexate, Warfarin, Phenytoin interactions
- Pregnant or breastfeeding women — consult doctor first
How Does Omeprazole GPO Compare to Other Acid Reducers?
Omeprazole GPO vs. Nexium (Esomeprazole): Nexium contains only the S-isomer (Esomeprazole), which some studies suggest may be slightly better in certain cases. However, the clinical difference is small. Nexium costs significantly more. Omeprazole GPO is a highly cost-effective option for long-term use.
Omeprazole GPO vs. Famotidine (H2 Blocker): Omeprazole is a PPI, which suppresses acid much more potently than H2 Blockers. Suitable for severe symptoms or ulcers. Famotidine is better for mild symptoms or occasional use.
How Long Does Omeprazole GPO Take to Work?
Omeprazole starts reducing acid within 1 hour, but it takes 2–5 days to feel noticeable improvement as the drug needs to accumulate and inhibit enough Proton Pumps.
Results timeline:
- Day 1: Acid reduction begins but may not be noticeable
- 2–5 days: Heartburn significantly improves
- 2–4 weeks: Ulcers begin to heal
- 4–8 weeks: Full healing for most patients
If symptoms don't improve within 2 weeks, consult your doctor.
Where Can I Buy Omeprazole GPO?
Omeprazole GPO is a pharmacist-dispensed medication. You can order online from Intimo Life.
Can I buy Omeprazole GPO online?
Yes. Order through Intimo Life — select the product, consult with a licensed pharmacist online, and receive your medication at home.
Do I need a prescription?
A doctor's prescription is not required, but the medication must be dispensed by a licensed pharmacist. At Intimo Life, our pharmacist will review your symptoms and health history to confirm suitability before shipping.
How does Intimo Life ship orders?
We deliver nationwide in Thailand with discreet packaging — no product names on the outside.
⚠️ Disclaimer
The information on this page is for general informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment from a qualified doctor or pharmacist. If you have any questions about your symptoms or medication, always consult a doctor or pharmacist first.
References
- StatPearls — Omeprazole. Shah N, Gossman W. NCBI Bookshelf. Updated February 2023.
- Johnsson F, et al. "High dose proton pump inhibitor response as an initial strategy for GERD diagnosis." European Journal of Gastroenterology & Hepatology. 2000.
- Omeprazole — NHS UK.
- Omeprazole (Oral Route) — Mayo Clinic.
- Omeprazole — Drugs.com. Updated 2024.
- Omeprazole — DrugBank Online.
- Omeprazole — MedlinePlus, U.S. National Library of Medicine.
Frequently Asked Questions
Very similar. Omeprazole GPO is racemic Omeprazole while Nexium is Esomeprazole (the S-isomer of Omeprazole). Some studies suggest Esomeprazole may be slightly better, but the clinical difference is minimal. Omeprazole GPO is significantly cheaper — ideal for long-term use.
Yes. Take 30 minutes before meals (especially breakfast) because Omeprazole works best when Proton Pumps are active, which happens during eating. Taking it after meals significantly reduces effectiveness.
Long-term PPI use (over 1 year) may increase risk of magnesium deficiency, vitamin B12 deficiency, bone fractures, and C. difficile infection. Use the lowest effective dose and attempt to taper off when symptoms improve. Consult your doctor regularly.
Not recommended. Omeprazole inhibits CYP2C19, the enzyme that converts Clopidogrel to its active form, reducing its effectiveness. If a PPI is needed with Clopidogrel, switch to Pantoprazole instead.
Yes. Abruptly stopping PPIs can cause Rebound Acid Hypersecretion — the stomach temporarily produces more acid than normal. Therefore, taper the dose gradually before stopping, such as taking it every other day before discontinuing.
Omeprazole is Pregnancy Category C — use only when benefits outweigh risks. No clear evidence of harm, but always consult a doctor first. For acid reflux during pregnancy, doctors may recommend antacids or H2 blockers first.
Related Products
Products with the same active ingredient or treating the similar condition.
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NexiumOriginal PPI with 24-hour acid control you can trust
✓ In stock890.00 ฿ /(฿63.57/tablet)
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