Cetrizin

Cetrizin is a bioequivalent generic formulation containing Cetirizine HCl 10 mg — a 2nd-generation H1-antihistamine approved by the Thai FDA.

• The Cetirizine molecule in Cetrizin is identical to Zyrtec — same absorption, efficacy, and duration of action as confirmed by bioequivalence testing
• Blocks peripheral H1 receptors with low CNS penetration, resulting in less sedation than 1st-generation antihistamines
• 24-hour duration of action enables once-daily dosing
• Manufactured by Thai GMP-certified pharmaceutical producer; 10 tablets per blister strip

Cetrizin is indicated for the following allergic conditions:

• Allergic Rhinitis — Seasonal and Perennial: runny nose, sneezing, nasal congestion, nasal and eye itching
• Chronic Idiopathic Urticaria — hives with intense itching and skin wheals
• Atopic Dermatitis — pruritus relief for daily comfort and sleep quality
• Allergic Conjunctivitis — tearing, eye itching, and conjunctival redness

Cetrizin is not a direct cough suppressant or decongestant, but does reduce allergic rhinitis-associated nasal congestion.

Recommended dosage for Cetrizin 10 mg:

• Adults and children 12 years and older: 10 mg (1 tablet) once daily, any time of day, with or without food
• Children 6-11 years: 5 mg (half tablet) once or twice daily based on body weight
• Renal impairment (CrCl 10-30 mL/min): Reduce dose to 5 mg per day
• Elderly: Standard adult dose with caution for renal function

Take Cetrizin at the same time each day (morning or evening) to maintain consistent 24-hour plasma Cetirizine levels. Store below 25 degrees Celsius.

Potential side effects of Cetrizin (Cetirizine):

• Common: Mild drowsiness, dry mouth, headache, fatigue
• Uncommon: Nausea, abdominal discomfort, palpitations
• Less sedating than: Cetrizin causes significantly less drowsiness than Chlorpheniramine or Brompheniramine due to lower CNS penetration
• Driving caution: Although low sedation risk, test personal response before driving or operating machinery, especially initially

Most side effects are mild and self-limiting; discontinuation is generally not required.

Contraindications and precautions for Cetrizin (Cetirizine):

• Contraindicated: Known hypersensitivity to Cetirizine, Hydroxyzine, or any formulation excipients
• Renal impairment: Cetirizine is primarily renally excreted — dose adjustment required for CrCl <30 mL/min
• Driving/operating machinery: Low sedation risk, but individual responses vary — assess tolerance initially
• Avoid alcohol: Potentiates sedative effects
• Children under 6 years: 10 mg tablet not recommended; use age-appropriate syrup formulation

Comparing Cetrizin (Cetirizine) with other antihistamines:

• Cetrizin vs Chlorpheniramine (CPM): Cetrizin causes significantly less drowsiness and lasts 24 hours vs 4-6 hours — much better for daily activities
• Cetrizin vs Loratadine: Both are 2nd-gen with comparable sedation profiles; Cetirizine often has a slightly faster onset
• Cetrizin vs Fexofenadine (Telfast): Fexofenadine has the lowest sedation of the class — preferred for those particularly sensitive to drowsiness
• Cetrizin vs Zyrtec: Identical active ingredient; Zyrtec is the original brand at a higher price; Cetrizin is a bioequivalent generic

Drug interactions to consider when using Cetrizin (Cetirizine):

• CNS Depressants: Sedatives, benzodiazepines, opioids — may enhance drowsiness; use with caution
• Alcohol: Significantly potentiates sedation — avoid concurrent use
• Anticholinergic drugs: Additive anticholinergic side effects (dry mouth, urinary retention)
• High-dose Theophylline: May slightly reduce Cetirizine clearance; not clinically significant at standard doses

Cetirizine undergoes minimal CYP450 metabolism, resulting in fewer drug-drug interactions compared to some other antihistamines.

Onset and duration of Cetrizin (Cetirizine) action:

• Onset: Within 1 hour of administration (peak plasma level at approximately 1-2 hours)
• Duration: 24 hours — once-daily dosing maintains therapeutic plasma levels throughout the day
• Acute allergy symptoms: Runny nose, sneezing, and itching typically improve within 1-2 hours
• Chronic urticaria: May require several days to weeks of consistent use before optimal benefit is achieved

How to buy Cetrizin?

Order online at Intimo Life with nationwide delivery across Thailand in 1-3 business days. Discreet packaging — no product name on the outer box for your privacy.