
Levocetirizine Dihydrochloride
Levocet (Levocetirizine 5mg) Antihistamine Tablet 10 tablets
Levocet — Levocetirizine Dihydrochloride 5mg, low-drowsiness antihistamine, 24-hour allergy relief
💊 Active: Levocetirizine Dihydrochloride 5mg
⏱️ Dose: 1 tablet once daily; onset within 1 hour
🍽️ Food: With or without food
📦 Pack: 10 tablets (1x10)
⚡ Benefit: Less drowsy than cetirizine; suitable during work hours
🌡️ Storage: Below 30°C, away from sunlight
Shipping
Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.
Product Description
Levocet (Levocetirizine Dihydrochloride 5 mg) is a third-generation antihistamine — the active enantiomer of cetirizine. It blocks H1-histamine receptors with roughly twice the affinity of cetirizine, delivering allergy relief at only 5 mg with less drowsiness due to minimal blood-brain barrier penetration.
- 📊 Levocet works within 1 hour and lasts about 24 hours — taken once daily
- 📊 Levocetirizine has roughly twice the receptor binding affinity of cetirizine, so 5 mg matches cetirizine 10 mg
- 📊 Chronic spontaneous urticaria affects around 1% of the population, with levocetirizine a first-line treatment
- 📊 Studies show levocetirizine significantly reduces itching, hives, and nasal allergy symptoms versus placebo
- 📊 Levocetirizine's somnolence rate is about 5–6%, among the lowest-drowsiness antihistamines
🏭 Manufacturer: Levocet | Thai FDA registered | Order at Intimo Life
⚠️ Consult a doctor or pharmacist before use if you have underlying conditions, are pregnant, or breastfeeding.
About Levocet
What is Levocet?
Levocet is a film-coated antihistamine tablet containing Levocetirizine Dihydrochloride 5 mg as its active ingredient. It belongs to the third generation of antihistamines.
Mechanism of action: Levocet selectively binds to H1-histamine receptors, preventing histamine from triggering allergic reactions. Levocetirizine is the active R-enantiomer of cetirizine, with approximately twice the receptor binding affinity — providing equivalent efficacy at the lower 5 mg dose.
Compared to earlier antihistamines, Levocet (levocetirizine) causes significantly less drowsiness, has minimal blood-brain barrier penetration, and lacks anticholinergic effects (no dry mouth, dry eyes, or constipation as seen with chlorpheniramine) — making it well-suited for daily use.
What conditions does Levocet relieve?
Levocet (Levocetirizine 5mg) is used to relieve allergy symptoms caused by the immune system's response to allergens.
- 🤧 Nasal congestion, sneezing, runny nose from allergic rhinitis
- 👁️ Red, itchy, watery eyes from dust, pollen, or pet dander allergies
- 🌿 Seasonal allergies (hay fever) and year-round allergic rhinitis
- 🔴 Urticaria (hives) — acute and chronic raised, red, itchy welts
- 🟠 Allergic skin reactions and itching
- 😤 Chronic allergies and perennial rhinitis
Levocet is ideal for those who need a low-drowsiness antihistamine for daily use without affecting work, driving, or tasks requiring concentration.
How to take Levocet — dosage guide
How to take Levocet (Levocetirizine 5 mg):
- Adults / children ≥12 yrs: 1 tablet (5mg) once daily, preferably evening
- Children 6–11 yrs: 2.5 mg twice daily (consult a doctor)
- Food: With or without; evening dosing reduces daytime drowsiness
- Max dose: 5 mg/day for adults
- Renal impairment / elderly: Dose adjustment may be needed; consult a doctor
- Missed dose: Take when remembered; skip if next dose is near — do not double up
Levocet works within 1 hour and lasts 24 hours from a single daily dose.
Side effects of Levocet
Levocet (levocetirizine) may cause side effects in some people, though these are generally mild and infrequent.
- Common (1–10%): Mild drowsiness, headache, dry mouth, nausea, fatigue
- Uncommon (0.1–1%): Dizziness, palpitations, mild constipation
- Rare (<0.1%): Difficulty urinating, visual disturbance, seizures (reported in young children)
Levocet (levocetirizine) causes less drowsiness than cetirizine because, as the active enantiomer, it binds receptors more selectively and has lower blood-brain barrier penetration.
Stop taking Levocet and seek immediate medical attention if you experience severe allergic reactions such as a severe rash, hives, difficulty breathing, or facial swelling.
Contraindications and Precautions
Contraindications and precautions for Levocet:
- ❌ Allergy to levocetirizine, cetirizine, hydroxyzine, or any ingredient
- ❌ Children under 6 years (tablet form)
- ❌ End-stage renal disease
- ⚠️ Renal impairment: adjust dose per creatinine clearance; consult a doctor
- ⚠️ Pregnancy / breastfeeding: consult a doctor first
- ⚠️ Elderly: increased sensitivity; start cautiously
- ⚠️ Driving: low-drowsiness but monitor your own reaction
- ⚠️ Alcohol / sedatives: may amplify drowsiness
Levocet vs other antihistamine tablets
Intimo Life stocks several antihistamine tablets. Here is a quick comparison:
- Levocet (Levocetirizine 5mg) — active enantiomer of cetirizine; lowest drowsiness in the cetirizine class; ideal for those who found cetirizine too sedating
- Cettec (Cetirizine) — non-drowsy antihistamine at the most affordable price; suitable for general use
- Alerest (Cetirizine) — same cetirizine active as Cettec; good value for regular use
- Telfast (Fexofenadine) — completely non-drowsy; best choice for drivers and those needing full concentration
Quick summary: Levocet (levocetirizine) offers the least sedation in the cetirizine class with the most targeted action — ideal if cetirizine (Cettec/Alerest) caused too much drowsiness; Cettec/Alerest (cetirizine) are the most affordable option; Telfast (fexofenadine) is zero-drowsiness for drivers and demanding workdays.
Can Levocet be taken with other medications?
Key drug interactions for Levocet (levocetirizine):
- Alcohol: Amplifies CNS depression; avoid
- Sedatives / sleeping pills: Additive drowsiness
- Other antihistamines: Avoid concurrent use
- Ritonavir: May raise levocetirizine blood levels
- Paracetamol / antibiotics: Generally safe; confirm with your pharmacist
Inform your pharmacist of all current medications before purchasing Levocet.
How quickly does Levocet work?
Levocet (levocetirizine 5 mg) provides rapid, sustained allergy relief:
- ⏱️ Onset of action: Within 1 hour of taking the tablet
- ⏱️ Peak effect: Approximately 0.9 hours (Tmax ≈ 0.9 h per pharmacokinetic data)
- ⏱️ Duration: Up to 24 hours — once-daily dosing
- ⏱️ Half-life: Approximately 8–9 hours; eliminated primarily via the kidneys
Levocet has near-100% oral bioavailability, allowing plasma levels to peak quickly and consistently — making it effective both for regular daily use and as-needed relief during acute allergy episodes.
Where to buy Levocet?
Where to buy Levocet?
Order Levocet (Levocetirizine 5mg) online at Intimo Life. We deliver nationwide across Thailand within 1-3 business days in discreet packaging — product name not printed on the parcel.
⚠️ Disclaimer
The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.
References
- Levocetirizine — MedlinePlus (NIH)
- Levocetirizine. MedlinePlus, U.S. National Library of Medicine. 2024.
- Antihistamines. NHS UK. 2024.
- Major role for the carboxylic function of cetirizine and levocetirizine in their binding characteristics to human H1-histamine-receptors
- Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use-A Scoping Review
Frequently Asked Questions
Levocet is not habit-forming and does not accumulate to harmful levels. It can be taken continuously during periods of active allergy symptoms — for example during weather changes or regular exposure to allergens. Once symptoms subside, it can be tapered off gradually. Daily use is not necessary if symptoms are mild or infrequent.
Levocet 5 mg tablets are suitable for adults and children aged 6 and above. For children aged 6–11, doctors typically recommend half a tablet (2.5 mg) once daily. Children under 6 should always be seen by a doctor first, as dosing may need to be adjusted by body weight.
Evening or bedtime dosing is recommended so that any mild drowsiness does not affect daytime activity. Levocet can be taken with or without food. The key is to take it at the same time each day to maintain a steady blood level.
Levocet (levocetirizine) causes less drowsiness than cetirizine because, as the active enantiomer, it binds H1-receptors more selectively with lower blood-brain barrier penetration. Most people experience no significant drowsiness, though some may feel mildly sleepy at first — switching to evening dosing usually resolves this.
Pregnant and breastfeeding women should consult a doctor before taking any antihistamine, including Levocet. Safety data in pregnancy is limited, so a doctor will weigh individual benefits against potential risks. Levocetirizine can pass into breast milk, making extra caution advisable during breastfeeding.
Dry mouth and dry throat can occur with some antihistamines, but Levocet (levocetirizine) is a third-generation antihistamine with very low anticholinergic activity, making these side effects far less likely than with first-generation options such as chlorpheniramine. If dryness does occur, increase fluid intake and inform your pharmacist or doctor so they can review your medication.
Levocetirizine is the active R-enantiomer of cetirizine, with approximately twice the receptor binding affinity — meaning 5 mg of levocetirizine delivers equivalent efficacy to 10 mg of cetirizine while causing less drowsiness. Cetirizine (e.g. Cettec, Alerest) is typically more affordable and suitable for general allergy relief.
Levocet can be used continuously as directed by a doctor or pharmacist. For chronic conditions such as perennial allergic rhinitis or chronic urticaria, courses of 4–8 weeks or longer are common. For seasonal allergies, it may be used only during symptomatic periods. Consult a doctor or pharmacist for use longer than 4 weeks.
If you miss a dose, take it as soon as you remember. However, if it is within 4–6 hours of your next scheduled dose, skip the missed dose and continue with your regular schedule. Never double up to make up for a missed dose, as this may increase the risk of side effects such as excessive drowsiness.
Related Products
Products with the same active ingredient or treating the similar condition.
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AlerestNon-drowsy 24-hour antihistamine
✓ In stock25.00 ฿ /(฿2.5/tablet) -
CetrizinGeneric Cetirizine antihistamine, cost-effective option
✓ In stockFrom 19.00 ฿ /(฿1.47/tablet) -
Cettec (Cetirizine Dihydrochloride 10mg) Non-Drowsy AntihistamineCetirizine 10mg for allergy, rhinitis & hives
✓ In stockFrom 19.00 ฿ /(฿1.69/tablet)
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