Myonal — A muscle relaxant that relieves muscle spasm, stiffness, and inflammation. Ideal for neck, shoulder, back pain, and spasticity from neurological conditions.
💊 Active ingredient — Eperisone Hydrochloride, a centrally acting muscle relaxant
💤 Less drowsiness — Compared to some older muscle relaxants, making it suitable for daytime use
🩸 Improves blood flow — Vasodilatory action helps increase circulation to tense muscles
📋 Take 1 tablet, 3 times daily after meals
📦 Packaged in boxes of 3 blisters (30 tablets)
🌡️ Store below 30°C — Protect from sunlight and moisture
Myonal is a muscle relaxant containing Eperisone Hydrochloride as its active ingredient. It belongs to the Centrally Acting Muscle Relaxant group and is used to relieve muscle spasm, stiffness, and pain from various causes — including Cervical Syndrome (neck, shoulder, and upper back pain), Lumbago (lower back pain), Periarthritis of the Shoulder, and spasticity from neurological conditions such as cerebrovascular disease or cervical spondylosis.
Eperisone works by inhibiting the vicious cycle of muscle spasm at the spinal cord level, reducing Muscle Spindle sensitivity, and providing vasodilatory action that improves blood flow to tense muscles. Its key advantage is causing less drowsiness compared to some older muscle relaxants such as Orphenadrine or Carisoprodol. Manufactured by Medinova AG, Switzerland, and distributed by DKS-H in Thailand.
To order Myonal, customers need to register an account with Intimo Life and consult with our pharmacist online to receive approval before placing an order through our website.
About Myonal
What is Myonal?
Biocalm is a muscle relaxant manufactured by Biolab Co., Ltd. in Thailand. Its active ingredient is Tolperisone Hydrochloride, classified as a Centrally Acting Muscle Relaxant.
Tolperisone was first developed in Hungary in the 1960s and has been widely used across Europe, Asia, South America, and Africa for decades. In Thailand, Biocalm is registered as a dangerous drug (Registration No. 1A 14/56), meaning it must be dispensed by a physician or pharmacist only.
Biocalm is used to relieve muscle pain, muscle inflammation, and muscle spasms from various causes, including:
Low back pain — One of the most common complaints among working adults
Neck, shoulder, and upper back stiffness — Often caused by prolonged sitting or office syndrome
Spondylosis — A degenerative condition commonly found in older adults
Muscle spasms from other neurological conditions — Such as multiple sclerosis and myelopathy, as determined by a physician
How Does Myonal Work?
Eperisone, the active ingredient in Myonal, works through 3 main mechanisms:
1. Inhibition of the Vicious Cycle of Myotonia
When muscles go into spasm, a vicious cycle occurs: muscle spasm → reduced blood flow → pain → more spasm. Eperisone breaks this cycle by inhibiting spinal reflexes and reducing Muscle Spindle sensitivity, allowing skeletal muscles to relax.
2. Vasodilatory Action
Beyond muscle relaxation, Eperisone also dilates blood vessels, improving blood flow to spastic muscles. This delivers more oxygen and nutrients to the affected area, promoting faster recovery. This property sets Eperisone apart from many other muscle relaxants.
3. Less Sedation Than Older Muscle Relaxants
Because Eperisone's mechanism focuses on muscle relaxation and vasodilation rather than broad CNS depression, it causes less drowsiness than some older muscle relaxants such as Orphenadrine or Carisoprodol. Clinical studies have shown that Eperisone has comparable efficacy to other muscle relaxants but with significantly fewer gastrointestinal side effects — only 5% compared to 21.25% in the comparator group.
The drug is rapidly absorbed after oral administration, has an onset of action within 4–6 hours, and is primarily excreted through urine.
How to Use Myonal?
For Adults (18 years and older)
Take 1 tablet, 3 times daily after meals
Can be taken with food or immediately after meals to reduce stomach irritation
Not recommended on an empty stomach
If symptoms are mild, the doctor may adjust the dosage accordingly
Do not use continuously for more than 7–10 days without consulting a doctor
For Children (under 18 years)
Safety and efficacy have not been established in children
Not recommended for use in children under 18 unless prescribed by a doctor
For Elderly Patients and Those with Kidney Disease
Dose reduction may be necessary as the body may eliminate the drug more slowly
Should be closely monitored by a physician
If You Miss a Dose
Take it as soon as you remember
If it is almost time for your next dose, skip the missed dose
Never double the dose
Additional Advice
Avoid alcohol while taking this medication as it may increase drowsiness
Use caution when driving or operating machinery as the drug may cause drowsiness in some patients
If symptoms do not improve within 5–7 days, stop the medication and consult a doctor
Gastrointestinal: nausea, stomach discomfort, loss of appetite, constipation or diarrhoea, dry mouth
Clinical studies have shown that Eperisone has a lower incidence of side effects compared to many other muscle relaxants, particularly gastrointestinal side effects.
Rare but Serious Side Effects (stop medication immediately)
Severe allergic reactions (Anaphylaxis) — hives, facial swelling, difficulty breathing
If you experience any unusual symptoms, stop the medication and consult a doctor or pharmacist immediately.
Warnings and Precautions for Myonal
Contraindications
Known hypersensitivity to Eperisone or any component of the formulation
Patients with Myasthenia Gravis — use with extreme caution
Special Populations
Pregnant women: Not recommended, especially during the first and third trimesters. Always consult a doctor.
Breastfeeding women: Eperisone is excreted in breast milk. Not recommended. If the drug must be used, breastfeeding should be discontinued.
Liver or kidney disease: Dose reduction may be necessary to prevent drug accumulation.
Elderly: May be more sensitive to side effects. Dose reduction may be considered.
Children under 18: Safety has not been established.
Drug Interactions
CNS depressants such as sleeping pills, anxiolytics, first-generation antihistamines — may enhance drowsiness
Alcohol — strictly avoid as it significantly increases the risk of severe CNS depression
Methocarbamol — reports of visual accommodation disturbances when used together
Overdose
Main symptoms include severe drowsiness, muscle weakness, low blood pressure, and confusion. There is no specific antidote — treatment is symptomatic and supportive. In severe cases such as difficulty breathing or loss of consciousness, seek emergency medical attention immediately.
Where to Buy Myonal?
Myonal is classified as a dangerous drug under Thai law and cannot be purchased at convenience stores. It must be obtained from a licensed pharmacy with a pharmacist on duty, or ordered online from an authorised retailer.
For convenience, you can order Myonal online from Intimo Life by following these simple steps:
Register an account on the Intimo Life website
Consult with our pharmacist online for a suitability assessment
Receive approval from the pharmacist
Place your order through the website
Benefits of ordering through Intimo Life include no need to visit a clinic or hospital, pharmacist consultation from home, and fast delivery to your door.
Frequently Asked Questions About Myonal
Can I take Myonal with Paracetamol or Ibuprofen?
Yes, Myonal can be taken alongside Paracetamol or NSAIDs such as Ibuprofen and Naproxen to enhance pain relief. A clinical study found that combining Eperisone with Ibuprofen was more effective at reducing pain than Ibuprofen alone. However, always consult a doctor or pharmacist before combining medications, especially if you have underlying health conditions.
Can Myonal treat herniated disc?
Myonal can help relieve muscle pain and spasm associated with a herniated disc, but it does not treat the underlying cause directly. It provides symptomatic relief only. Consult a doctor for a comprehensive treatment plan.
Is Myonal addictive?
No. Eperisone is not classified as a narcotic or addictive substance. There are no reports of addiction or dependence from normal use. You can stop taking it once symptoms improve without needing to taper the dose.
Can Myonal cause low blood pressure?
Low blood pressure is a possible but uncommon side effect, usually occurring at higher doses or in patients who are particularly sensitive. Be cautious of dizziness when changing positions, especially from sitting or lying down to standing.
Can Myonal treat migraines?
Myonal is not a migraine treatment. However, it may be used in some patients whose migraines are accompanied by neck and shoulder muscle tension (tension-type headache associated with migraine). Consult a doctor for proper diagnosis and appropriate medication.
How long does Myonal last?
Eperisone's effects last approximately 4–6 hours per dose, which is why it needs to be taken 3 times daily to maintain coverage throughout the day.
How is Myonal different from Norgesic or Mydocalm?
Myonal (Eperisone) stands out for its vasodilatory action that improves blood flow to tense muscles, in addition to its muscle relaxant effect. It also tends to cause less drowsiness than some older muscle relaxants like Orphenadrine (found in Norgesic). Mydocalm (Tolperisone) is in the same drug class with a similar chemical structure, but each has its own advantages. Consult a doctor or pharmacist to choose the most suitable option.
Can I take Myonal on an empty stomach?
Not recommended. To reduce the risk of stomach irritation, take Myonal immediately after meals or with food.
Can I stop Myonal on my own?
If you have been using it short-term for symptom relief and your symptoms have improved, you can stop without tapering. However, if you have been using it for an extended period and symptoms persist, consult a doctor.
How should I store Myonal?
Store in the original blister pack at room temperature not exceeding 30°C. Protect from sunlight, heat, and moisture. Keep out of reach of children and pets.
Biocalm
Mydocalm
Norgesic
