Biocalm

Biocalm is a film-coated muscle relaxant tablet containing Tolperisone Hydrochloride as its active ingredient. It belongs to the Centrally Acting Muscle Relaxant class — the same active ingredient found in Mydocalm.

Tolperisone works by inhibiting voltage-gated sodium and calcium channels in the nervous system, reducing nerve impulses that cause muscle contraction and spasm. A key advantage is that Tolperisone does not significantly affect the cerebral cortex, resulting in significantly less sedation compared to older muscle relaxants — a double-blind study in 72 volunteers found no sedative effects at any measurement point.

Muscle pain, spasm, and inflammation from various causes, including:

• Low back pain — The most common complaint in working-age adults
• Neck, shoulder, and upper back tension / Office syndrome — Often caused by prolonged sitting and poor posture
• Spondylosis — Common in older adults
• Arthrosis — Pain and stiffness in major joints
• Post-stroke spasticity — Helps reduce abnormally increased muscle tone, improving mobility

See other options in our muscle relaxant collection.

Take 1–3 tablets three times daily, immediately after meals. Swallow whole with water. Do not break, crush, or chew as this is a film-coated tablet.

Starting the medication: Begin with a low dose and gradually increase as directed by your doctor or pharmacist.

Duration: Do not use for more than 3–5 consecutive days without medical advice. If symptoms do not improve, consult your doctor.

Missed dose: Take it as soon as you remember. If it is almost time for the next dose, skip the missed one. Never double the dose.

Elderly / liver or kidney disease: Consult your doctor for dose adjustment, as the drug is metabolized by the liver and excreted through the kidneys.

Children under 18: Not recommended due to insufficient safety data.

Side effects of Biocalm are uncommon. In a large post-marketing study of 920 patients, no sedation was reported, and other side effects such as nausea occurred in less than 2% of users.

Possible side effects (uncommon):

• Fatigue, headache, dizziness
• Nausea, stomach discomfort, dry mouth
• Low blood pressure (rare)
• Muscle weakness (rare)

Stop the medication and seek medical attention immediately if:

• Rash, itching, or swelling of the face or throat
• Difficulty breathing or wheezing
• Severe drop in blood pressure, fainting
• Anaphylaxis — extremely rare but requires immediate medical attention

Do not use:

• If allergic to Tolperisone or structurally similar drugs such as Eperisone
• If you have Myasthenia Gravis
• If you have severe liver or kidney impairment
• During pregnancy or breastfeeding — insufficient safety data
• If under 18 years of age

Use with caution:

• Avoid alcohol — may enhance sedative effects
• Be cautious when driving, especially when first starting the medication, even though Tolperisone causes less sedation than older alternatives

Biocalm vs. Mydocalm: Same active ingredient (Tolperisone), identical mechanism of action. Mydocalm is manufactured by Gedeon Richter (Hungary), while Biocalm is a Thai-manufactured equivalent by Biolab.

Tolperisone (Biocalm) vs. Eperisone (Myonal):

Tolperisone (Biocalm) — Centrally acting muscle relaxant with minimal sedation. Taken 3 times daily. Clinical studies confirm no sedative effects in psychomotor testing.

Eperisone (Myonal) — Structurally similar muscle relaxant, also with minimal sedation. Improves blood circulation. Also taken 3 times daily.

Tolperisone vs. Orphenadrine (Norgesic):

Orphenadrine (Norgesic) — Combined muscle relaxant with paracetamol. Fast-acting but has significantly more anticholinergic effects (dry mouth, blurred vision, drowsiness) than Tolperisone.

See all options in our muscle relaxant collection.

Tolperisone has relatively few clinically significant drug interactions — an advantage over other muscle relaxants. However, caution is advised with certain medications:

Use with caution:

• Other CNS depressants such as benzodiazepines, sleeping pills, opioid painkillers — may enhance sedative effects
• NSAIDs such as Ibuprofen, Diclofenac — can be used together but monitor for gastrointestinal side effects

Safe to combine:

• Paracetamol — safe to use together; a commonly prescribed combination

Always inform your doctor or pharmacist about all medications you are currently taking before starting Biocalm.

Tolperisone is rapidly absorbed from the gastrointestinal tract. It begins working within approximately 30–60 minutes and reaches peak blood levels in about 1.5 hours.

It has an initial half-life of approximately 2 hours and a terminal half-life of about 12 hours. The drug is metabolized in the liver and primarily excreted through the kidneys.

Since it is taken three times daily, the medication provides coverage throughout the day when taken as directed.

Biocalm is classified as a dangerous drug under Thai pharmaceutical law. It must be dispensed by a doctor or pharmacist. You can order Biocalm online from Intimo Life without visiting a pharmacy in person.

Can I buy Biocalm online?

Yes. Order through Intimo Life — simply select your product, consult with a licensed pharmacist online, and receive your medication at home.

Do I need a prescription?

A doctor's prescription is not required, but the medication must be dispensed by a licensed pharmacist. At Intimo Life, our pharmacist will review your health history to confirm it is safe and suitable for you before shipping.

How does Intimo Life ship orders?

We deliver nationwide in Thailand with discreet packaging — no product names on the outside.