Sodium Alginate + Potassium Bicarbonate

Gaviscon Advance Double-Strength Acid Reflux Liquid

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Gaviscon Advance — orange-labelled liquid antacid for nighttime acid reflux relief

💊 Active: Sodium Alginate, Potassium Bicarbonate
⏱️ Dosage: 5-10 ml after meals and at bedtime, up to 4 times/day
🍽️ Timing: Take after meals only
📦 Pack: 150 ml bottle or box of 24 sachets
⚡ Benefit: 2x alginate concentration, thicker raft lasting up to 4 hours
🌡️ Storage: Below 30°C, away from sunlight

Option: Volume 150 ml
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What is Gaviscon Advance?

Gaviscon Advance is an orange-labelled liquid antacid from the Gaviscon range. Its active ingredients are Sodium Alginate at twice the concentration of the standard formula, combined with Potassium Bicarbonate, forming a thick raft that blocks acid reflux for up to 4 hours. It relieves heartburn when taken after meals and at bedtime, 5-10 ml per dose.

🛒 150 ml bottle or 24 sachets · authentic · 24-hour dispatch from Intimo Life — consult a doctor or pharmacist before use.

Product Description

An acid reflux medicine, Gaviscon Advance is the extra-strength formula in the Gaviscon range: Sodium Alginate at twice the concentration of the standard formula, combined with Potassium Bicarbonate, forming a thick raft that blocks acid reflux for up to 4 hours. It suits nighttime heartburn or large-meal symptoms, using a smaller dose than standard Gaviscon (5-10 ml vs 10-20 ml).

📊 Key facts about acid reflux and alginate therapy

  • Global GERD prevalence in 2021: 825.6 million cases (GBD 2021, PMC12283765)
  • A meta-analysis of 14 alginate trials (2,095 patients) found significantly better symptom relief than placebo or plain antacids (Leiman et al. 2017, PMC6036656)
  • Advance has the lowest sodium content in the Gaviscon range, using Potassium Bicarbonate instead of Sodium Bicarbonate
  • For daily chronic reflux: Nexium controls acid all day; Advance suits acute relief, especially before bed

🏭 Manufactured by Reckitt Benckiser Healthcare (UK) Limited. Distributed in Thailand through DKSH.

⚠️ People with kidney disease or who monitor blood potassium should consult a pharmacist before use.

Supatcheree A., Pharmacist

Medically reviewed by

Supatcheree A., Pharmacist | Sources: NHS, EMC SmPC, MIMS, PubMed

Last reviewed: 2026-07-04

About Gaviscon Advance

What is Gaviscon Advance?

Gaviscon Advance is the orange-labelled, extra-strength formula in the Gaviscon range. What sets it apart is a Sodium Alginate concentration twice as high as the standard formula.

How it works: On contact with stomach acid, Sodium Alginate reacts instantly to form a thick, sticky raft that floats above the stomach contents. This raft acts as a physical barrier that blocks acid from refluxing into the oesophagus. Because of the higher concentration, the raft is thicker and longer-lasting than standard formulas, persisting for up to 4 hours.

Another key difference is the use of Potassium Bicarbonate instead of the Sodium Bicarbonate used in other formulas, giving Gaviscon Advance the lowest sodium content in the entire Gaviscon range. It suits people with severe heartburn or frequent nighttime symptoms.

What does Gaviscon Advance treat?

Gaviscon Advance relieves symptoms of acid reflux and excess stomach acid, particularly when severe or disruptive to sleep:

  • Nocturnal heartburn — lying flat makes acid reflux more likely; the thicker raft gives overnight protection
  • Sour or bitter reflux — acid rising to the throat
  • Heartburn after large or fatty meals — meals that trigger more acid need a thicker, longer-lasting raft
  • Pregnancy-related reflux — Advance has the lowest sodium in the Gaviscon range, so it is often recommended first; consult your doctor or pharmacist before use

Gaviscon Advance is not the primary treatment for daily chronic reflux, which may need a PPI alongside lifestyle changes.

How to take Gaviscon Advance — Dosage

Dosage for adults and children aged 12 and over:

  • Take 5-10 ml (1-2 of the supplied measuring spoons) after each of 3 meals and before bedtime
  • Maximum 4 doses per day
  • Shake the bottle before each use; sachets can be taken directly without shaking

Note that the per-dose volume of Gaviscon Advance is smaller than the standard formula's 10-20 ml, because its alginate concentration is twice as high — less liquid, same effect.

When should you take Gaviscon Advance? Take it immediately after meals or within 20-30 minutes, and always before bedtime. Avoid taking it on an empty stomach, as the raft forms thinner and works less well.

Do not use Gaviscon Advance for more than 7 consecutive days without consulting a pharmacist if symptoms do not improve or worsen.

Gaviscon Advance side effects

Gaviscon Advance is generally well tolerated as it is not absorbed into the bloodstream, though mild side effects can occur:

  • Bloating and burping — from bicarbonate reacting with stomach acid, releasing CO₂ gas
  • Mild nausea — occasional, especially with doses above the recommended amount
  • Constipation — less common than with higher-calcium-carbonate formulas

People with kidney problems should be cautious due to its potassium. If signs of allergy occur — rash or breathing difficulty — stop use and see a pharmacist immediately.

Contraindications / Precautions for Gaviscon Advance

Contraindications:

  • Known allergy to any ingredient, including Sodium Alginate or Potassium Bicarbonate
  • Children under 12 — the adult formulation is not recommended without medical advice

Precautions:

  • Kidney disease or medicines that affect potassium (e.g. potassium-sparing diuretics) — consult a doctor first, since Advance contains potassium as a key ingredient
  • Pregnancy — generally safe, but consult your doctor or pharmacist first
  • Other medications — take Advance at least 2 hours apart, as the raft may slow their absorption
  • Do not use beyond 7 consecutive days without a pharmacist; seek medical care immediately for difficulty swallowing or vomiting blood

How Does Gaviscon Advance Compare to Other Acid Reflux Medicines?

Different acid reflux medications suit different symptom levels:

What makes Advance different: twice the alginate concentration, a smaller dose, and the lowest sodium content in the Gaviscon range — best suited for severe or nighttime symptoms.

Simple guide: Severe/nighttime symptoms → Gaviscon Advance | General post-meal symptoms → Peppermint or Dual Action | Daily chronic reflux → a PPI such as Omeprazole GPO or Nexium

How Do the Different Gaviscon Colours Differ?

Each Gaviscon colour is a different formula, not just a different flavour: green (Peppermint) is the original formula, pink (Dual Action) combines raft formation with acid neutralising, and orange (Advance) — this product — has twice the alginate concentration for severe or nighttime symptoms. Read the full colour comparison at our Gaviscon guide

How Quickly Does Gaviscon Advance Work?

Gaviscon Advance works quickly — an immediate chemical reaction, not requiring absorption:

  • Relief typically begins once the raft has formed and blocked the acid
  • Lasts up to 4 hours — longer than the standard formula's 2-4 hour range, since the doubled alginate concentration forms a thicker, slower-breaking raft
  • Compared to PPIs like Omeprazole or Nexium, which need 1-4 weeks for full effect, Advance suits acute relief while waiting for a PPI, or for occasional symptoms alone

If symptoms do not improve within 30 minutes, or are severe, consult a pharmacist.

Where Can I Buy Gaviscon Advance?

Where to buy Gaviscon Advance?

Order online at Intimo Life. We deliver across Thailand within 1-3 business days. All orders are packed discreetly — no product name printed on the outer packaging.

⚠️ Disclaimer

The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.

Frequently Asked Questions

Gaviscon Advance is generally considered safe in pregnancy, as Sodium Alginate is not absorbed and does not cross the placenta. NHS UK lists Gaviscon as a recommended option for pregnancy reflux, and Advance is often a first choice since it has the lowest sodium in the range. Always consult your doctor or pharmacist before continued use.

Gaviscon Advance has twice the alginate concentration of the standard formulas (Peppermint, Dual Action) and uses Potassium Bicarbonate instead of Sodium Bicarbonate, giving lower sodium. Consider switching if the standard formula isn't giving enough relief, you get frequent nighttime heartburn, or symptoms are severe after large meals. For mild, occasional symptoms, the standard formula is usually enough.

Most people feel relief within 3-5 minutes, as Sodium Alginate reacts with stomach acid immediately without needing absorption. If heartburn persists after 15-20 minutes, repeat the recommended dose, but do not exceed 4 doses a day.

Take it as soon as you remember. This antacid does not need a steady blood level like chronic medications, so a delayed dose is not dangerous. Do not double up to compensate — stick to the normal 5-10 ml amount.

The adult formulation is not recommended for children under 12, as the dose and alginate concentration are designed for adults. If your child has reflux or frequent spit-up, see a paediatrician for age-appropriate product and dosing advice.

For people with normal kidney function, the potassium in each dose is not a concern. However, people with chronic kidney disease or reduced potassium excretion may develop dangerously high blood potassium, which can affect the heart. These patients should consult a doctor first and may need a potassium-free formula instead.

Not recommended. The maximum is 4 doses a day (after each of 3 meals and at bedtime). Exceeding this may increase side effects like bloating or excess sodium and potassium intake. If symptoms persist, consult a pharmacist rather than increasing the dose yourself.

Gaviscon Advance comes as a 150 ml bottle or a box of 24 sachets. The bottle usually costs less per ml, suiting regular home use, while sachets are more portable, though they cost more per dose. Check the current price on the Intimo Life product page.

Once opened, use within 1-2 months and store below 30°C away from sunlight. If the colour, smell, or texture changes, stop using it, and always check the expiry date on the label too.

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