Uniren Spray

Uniren Spray is a topical NSAID spray containing Diclofenac Sodium 4%. It acts as a selective COX inhibitor to reduce local inflammation and provide targeted pain relief directly at the injury site.

Two key mechanisms:

• COX-1/COX-2 inhibition: Reduces prostaglandin synthesis — the inflammatory mediators responsible for pain and swelling at injured tissue
• Localised action: Uniren Spray penetrates into deep tissue layers with minimal systemic absorption, substantially reducing the risk of systemic side effects

Manufactured by Unison Laboratories, Thailand, in a 60 ml bottle. Indicated for muscle pain, sprains, and soft tissue injuries.

Uniren Spray (Diclofenac Sodium 4%) is indicated for:

• Localised muscle pain: Exercise-related soreness, heavy-lifting injuries, localised lower back pain
• Sprains and ankle twists: Acute soft tissue injury — reduces swelling and pain rapidly
• Localised joint pain: Mildly inflamed joints including the knee, wrist, and fingers
• Sports injuries: Quick targeted relief for athletes with localised musculoskeletal complaints

Not suitable for generalised body pain, severe arthritic conditions, or cases requiring systemic therapy. Consult a doctor for these conditions.

How to apply Uniren Spray correctly:

• Clean and dry the skin over the affected area
• Hold the bottle 10-15 cm from skin; spray 1-2 actuations per area to cover the painful site
• Apply 3-4 times daily, at least 4 hours apart; do not exceed 4 applications per day
• Do not rub after spraying — the formula absorbs without friction
• Wash hands after each application unless the hands are the treated area

Duration: For acute injury up to 7 days. For chronic joint pain up to 14 days under medical supervision. If a dose is missed, apply when remembered; skip if nearly time for the next dose — never increase the number of sprays to compensate.

Common side effects of Uniren Spray (topical Diclofenac Sodium):

• Mild skin redness or irritation: Most common; typically resolves within 1-2 hours of application
• Dryness or mild itch: Occasional in sensitive skin; applying a moisturiser at a different time from the spray helps
• Solvent inhalation: Use in a well-ventilated area to avoid inhaling propellant

Less common but notable: contact dermatitis with marked swelling, intense redness, or blistering — discontinue and rinse with clean water immediately. A key advantage of Uniren Spray is very low systemic absorption, substantially reducing gastrointestinal and renal side-effect risks compared with oral NSAIDs.

Contraindications:

• Hypersensitivity to Diclofenac or other NSAIDs such as aspirin or ibuprofen
• Do not apply to open wounds, infected skin, or sunburned areas
• Avoid contact with eyes, lips, mucous membranes, or skin affected by eczema or allergic rash
• Do not use under occlusive dressings
• Third trimester of pregnancy — absolutely contraindicated

Precautions: Consult a doctor before use in the first or second trimester or when breastfeeding. Insufficient safety data exist for children under 14. Use with caution in severe hepatic or renal impairment. Cross-reactivity with aspirin-sensitive individuals is possible.

Uniren Spray (Diclofenac Sodium) is a topical NSAID spray targeting pain and inflammation through prostaglandin inhibition, distinct in mechanism from the other topicals in the Intimo store which focus on bruise resolution and vascular support.

• Uniren Spray (Diclofenac Sodium) — Topical NSAID for musculoskeletal pain and inflammation Inhibits COX-1/COX-2 to reduce local prostaglandin synthesis, delivering targeted analgesia and anti-inflammatory action. Spray format eliminates the need to rub the painful area. Best suited for muscle strains, sprains, and inflammatory joint pain.
• Reparil Gel N (Aescin + Diethylamine Salicylate) — Natural vascular-support gel for acute bruising Aescin strengthens capillary walls and limits oedema formation. Not an NSAID; offers milder analgesia but is more targeted for soft-tissue bruising and post-impact swelling.
• Hirudoid (Mucopolysaccharide Polysulfate) — Haematoma resorption and tissue remodelling gel Heparin-like action accelerates breakdown of subcutaneous haematomas and supports connective tissue regeneration. Preferred for persistent or slow-resolving bruises. Does not provide NSAID-level analgesia.

Bottom line: For musculoskeletal pain, sprains, or joint inflammation, Uniren Spray is the most direct treatment. For fresh bruising with swelling, Reparil Gel N is more appropriate. For lingering haematomas, Hirudoid offers the best resolution support.

Key drug interactions with Uniren Spray (Diclofenac Sodium):

• Oral NSAIDs (ibuprofen, aspirin): Avoid concurrent use — although Uniren Spray has low systemic absorption, combining with oral NSAIDs may compound gastrointestinal side-effect risk
• Anticoagulants (warfarin): Exercise caution — Diclofenac may modestly potentiate anticoagulant effects
• Other topical medications: Do not apply over the same area simultaneously — may increase absorption and skin irritation
• Diuretics and antihypertensives: Minor reduction in efficacy possible if systemic absorption occurs

Because Uniren Spray provides substantially lower systemic exposure than oral NSAIDs, interaction risks are significantly reduced. Nevertheless, inform your doctor of all current medications.

Expected onset and timeline for Uniren Spray:

• First 30-60 minutes: Cooling and localised relaxation as Diclofenac Sodium begins penetrating the skin
• 2-4 hours: Tissue Diclofenac levels reach peak concentration — clear pain relief and anti-inflammatory effect
• Days 3-5: Treatment effect on acute soft tissue injury becomes evident — significant reduction in swelling and pain
• Day 7: Clinical studies show topical Diclofenac reduces VAS pain scores by 50-60% over 7 days for soft tissue injuries

Apply Uniren Spray consistently 3-4 times daily for 5-7 days to achieve optimal results. Do not discontinue early if improvement appears quickly — underlying inflammation may not yet be fully resolved.

How to buy Uniren Spray?

Order online at Intimo Life with nationwide delivery across Thailand in 1-3 business days. Discreet packaging — no product name on the outer box for your privacy.