Sildenafil

Sildenafil is the generic name for the well-known brand Viagra. Both Sildenafil and Viagra contain the same active ingredient, sildenafil citrate, which is used to treat erectile dysfunction (the inability to achieve or maintain an erection sufficient for sexual activity). Additionally, in some cases, specialists may use Sildenafil to manage pulmonary hypertension or certain types of stomach ulcers.

Sildenafil typically comes in tablet form, although in some countries liquid or gel forms may be available. For treating erectile dysfunction, the tablet form is the most commonly used and provides reliable results comparable to the original Viagra brand.

Sildenafil belongs to a popular class of sexual performance enhancers called PDE-5 inhibitors (phosphodiesterase type-5 inhibitors). These medications work by increasing blood flow to certain parts of the body, including the penis, making it easier to achieve and maintain an erection when sexually stimulated.

The main mechanism is that Sildenafil inhibits the enzyme PDE-5, which normally reduces blood flow to the penis. By blocking this enzyme, blood flow improves, resulting in easier and longer-lasting erections.

This medication contains the same active ingredient as Viagra, commonly known as sildenafil.

How Long Does Sildenafil Last?

Generally, Sildenafil works for about 4–6 hours, though this can vary between individuals. This means that if you are sexually aroused during this period, Sildenafil will help you achieve and maintain an erection more easily.

However, this does not mean the erection lasts 4–6 hours continuously. The duration refers to the time the medication remains effective. The best way to know how it works for you and how long it lasts is to try it as directed and observe your own response.

How Quickly Does Sildenafil Work?

Sildenafil typically takes about 30–60 minutes to start working. It is recommended to take it about 1 hour before sexual activity. Although the effect can last up to 6 hours, the peak effect usually occurs around 1 hour after taking the pill.

Taking Sildenafil immediately after a meal may delay its onset because food slows absorption.

How Effective Is Sildenafil?

Research shows that Sildenafil is effective for most men with erectile dysfunction. On average, about 69% of men using Sildenafil successfully engage in sexual intercourse, compared to 35.5% in the placebo group.

While Sildenafil helps achieve and maintain erections, it may not be suitable for everyone. The best way to know is to try it as directed and see how your body responds.

You should swallow the Sildenafil tablet whole with water or fruit juice. Do not take it with grapefruit juice, as it can affect the medication’s effectiveness. The medication works best when taken on an empty stomach. Although it can be taken safely with food, this may delay its onset. It is recommended to take it about 1 hour before sexual activity.

Sildenafil Dosage

Sildenafil tablets come in three strengths: 25 mg, 50 mg, and 100 mg. You should take only the dose recommended by your healthcare professional. The commonly used dose is 50 mg, taken no more than once per day when needed. This dose can be adjusted based on your body’s response:

• If 50 mg is not fully effective and there are no concerning side effects, the dose may be increased to 100 mg.
• If 50 mg works well but causes bothersome side effects, the dose may be reduced to 25 mg to minimize side effects while still aiding erection.

When Should I Take Sildenafil?

Take it about 1 hour before sexual activity, as it takes at least 30 minutes to start working. Remember that if taken after a meal, the onset may be delayed, so allow extra time.

How Often Can I Take Sildenafil?

Take Sildenafil only when needed (when planning sexual activity) and do not take more than once in 24 hours, as this may increase the risk of serious side effects. However, you may take it daily if necessary.

How Long Should I Take Sildenafil?

Take it only when you need help with erections for sexual activity. If you do not have erectile problems or do not plan to have sex, there is no need to take the medication.

Sildenafil is not a cure for erectile dysfunction but a support to improve erections. If your erectile issues improve through lifestyle changes or other factors, you may find you no longer need Viagra or Sildenafil.

Like most medications, Sildenafil may cause side effects in some people, but not everyone experiences them. Most side effects are mild and go away on their own, though serious side effects can also occur. They are categorized by frequency as follows:

Common side effects (affecting more than 1 in 100 people):

• Headache, dizziness
• Nausea, upset stomach, diarrhea
• Nasal congestion or other nasal issues
• Visual disturbances
• Hot flashes, night sweats
• Insomnia, nervousness
• Swelling in arms or legs

Uncommon side effects (affecting fewer than 1 in 100 people):

• Vomiting
• Dry mouth, dry eyes
• Chest pain, palpitations, irregular heartbeat
• High blood pressure
• Tinnitus (ringing in the ears)
• Enlarged breasts in men (gynecomastia)
• Fatigue

Rare or very rare side effects (affecting fewer than 1 in 1,000 people):

• Blood in semen
• Fainting or lightheadedness
• Severe vision problems (e.g., glaucoma, retinal disorders)
• Prolonged and painful erections (priapism)
• Seizures, stroke, or heart attack
• Severe skin reactions

How long do side effects last?

Most side effects from Viagra or Sildenafil usually resolve within 1 day. For example, headaches often improve as your body adjusts. If symptoms persist or interfere with daily life, consult a healthcare professional immediately.

What to do if side effects occur?

For mild symptoms, you can manage them at home as follows:

• Headache: Drink plenty of water to stay hydrated
• Nausea: Avoid spicy or fatty foods
• Flushing/hot flashes: Avoid alcohol and caffeine
• Dizziness: Lie down and rest
• Nasal congestion: Use a nasal spray to ease breathing

Serious symptoms requiring immediate medical attention:

• Seizures
• Chest pain
• Prolonged and painful erection lasting more than 2 hours

When using Viagra or Sildenafil, start with the appropriate dose to minimize these risks and ensure safe and effective use every time.

You should not use Sildenafil if you fall into any of the following categories:

• Allergic to sildenafil
• Currently using nitrate medications (commonly used for chest pain/angina)
• Have bleeding disorders or conditions causing easy bleeding (e.g., hemophilia)
• Have penile abnormalities or Peyronie’s disease (curved penis)
• Have rare inherited eye diseases (e.g., retinitis pigmentosa)
• Have severe heart or liver problems
• Have stomach ulcers
• Have low blood pressure
• Recently experienced a heart attack, heart problems, or stroke
• Have sickle cell anemia, leukemia, or multiple myeloma

If you are unsure whether Viagra or Sildenafil is suitable for you, it is recommended to consult a healthcare professional or pharmacist before starting to ensure safety.

Can I drink alcohol while using Sildenafil?

You can drink alcohol, but it is advisable to avoid or limit consumption because alcohol may make it harder to achieve and maintain an erection and increase the risk of side effects. For the best results with Viagra or Sildenafil, it is better to avoid alcohol.

How often can I take Sildenafil?

You should not take Sildenafil more than once per day and only as directed by a healthcare professional. Taking it too frequently increases the risk of serious side effects.

Does Sildenafil help delay ejaculation or increase stamina?

Sildenafil may help delay ejaculation if you have both erectile dysfunction and premature ejaculation. If premature ejaculation is your only concern, other treatments may be more appropriate. However, if your main issue is maintaining an erection until ejaculation, Sildenafil can help you last longer.

Does Sildenafil make the penis bigger?

Sildenafil helps you achieve a fuller erection if you have erectile dysfunction but does not increase the natural size of the penis. It is not a penis enlargement drug.

Is Sildenafil cheaper than Viagra?

Yes, Sildenafil is the generic form of Viagra, so it does not carry a brand name and is therefore less expensive than branded Viagra but offers similar results.

Is Sildenafil stronger than Viagra?

No, Sildenafil and Viagra contain the same active ingredient and come in the same dosages. When taken at the same dose, their effectiveness and strength are equal. There is no stronger version on either side.

Can women use Sildenafil?

Currently, there is no clear evidence that Sildenafil helps with sexual problems in women, and in Thailand, Sildenafil is not approved for use by women for sexual issues.