Zema Cream — Econazole Nitrate 1%, broad-spectrum antifungal for ringworm, versicolor and Candida
💊 Econazole Nitrate — targets dermatophytes, Candida, Malassezia
⏱️ Apply 1-2x daily; continue 2-4 weeks full course
🍽️ Apply to clean dry skin; no meal timing needed
📦 10 g tube; Pharma International Co.
⚡ Covers ringworm, versicolor, jock itch, athlete's foot, Candida
🌡️ Store below 30°C; keep away from children
Shipping
Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.
Product Description
Antifungal cream Zema Cream contains Econazole Nitrate 1%, an Imidazole antifungal that inhibits ergosterol synthesis in fungal cell walls, effectively eliminating dermatophytes (ringworm, jock itch, athlete's foot), Candida albicans (cutaneous candidiasis), and Malassezia furfur (pityriasis versicolor) with a single product.
📊 Fungal skin infections (Dermatophytosis) affect approximately 20–25% of the world population — WHO Global Health Observatory 2022
📊 Ringworm (Tinea corporis) is the 3rd most common fungal skin disease in tropical countries including Thailand
📊 Econazole Nitrate achieves clinical cure rates >85% in Tinea pedis and Tinea corporis per Cochrane meta-analysis (2017)
📊 Athlete's foot (Tinea pedis) affects up to 15% of gym and pool users who wear enclosed footwear for prolonged periods
🏭 Manufacturer: Pharma International Co., Ltd. | Registration No. 1A 205/49 | Made in Thailand
⚠️ Consult a pharmacist if symptoms do not improve within 2 weeks, or if signs of allergic reaction occur such as excessive redness or swelling.
Medically reviewed by
ทีมเนื้อหา Intimo Life | Sources: WHO, NHS, DermNet, Cochrane
Last reviewed: 2026-06-04
About Zema Cream
What is Zema Cream?
Zema Cream is an antifungal topical medication containing Econazole Nitrate 1%, an Imidazole antifungal. Its mechanism of action involves blocking ergosterol synthesis, a critical component of fungal cell membranes. Without ergosterol, the fungal cell wall becomes compromised and the organism dies.
Econazole has a broad spectrum of activity covering:
Candida albicans — causing cutaneous candidiasis in skin folds and moist areas
Malassezia furfur — causing pityriasis versicolor (white/brown/pink patches on the trunk)
Zema Cream has a light, non-greasy texture that is easy to apply to any body area including the groin and between toes.
What does Zema Cream treat?
Zema Cream (Econazole Nitrate 1%) is used to treat the following fungal skin infections:
Ringworm (Tinea corporis) — Red, ring-shaped, itchy patches on arms, legs, or trunk
Pityriasis versicolor (Tinea versicolor) — White/brown/pink discoloured patches on chest, back, or upper arms caused by Malassezia
Jock itch (Tinea cruris) — Red, itchy rash in the groin and inner thighs
Athlete's foot (Tinea pedis) — Peeling, itching, cracking skin between toes or on the sole
Onychomycosis — Thickened, brittle, discoloured nails (used adjunctively)
Cutaneous candidiasis — Red rash in moist skin folds such as armpits or under the breast
Zema Cream is ideal for those seeking a broad-spectrum antifungal that covers multiple infection types in one product. Consult a pharmacist to confirm diagnosis before use.
How to apply Zema Cream / Dosage
How to use Zema Cream:
Wash hands and the affected area, then dry thoroughly before applying
Squeeze a small amount and apply a thin layer over the affected area and about 1-2 cm around it
Apply 1-2 times daily (morning and evening)
Continue the full course even if symptoms improve before the course is complete
Recommended treatment duration:
Ringworm / Jock itch: 2–4 weeks
Athlete's foot: 4 weeks
Pityriasis versicolor: 2–4 weeks (skin colour may take months to even out)
Cutaneous candidiasis: 2–4 weeks
⚠️ Avoid contact with eyes. Do not ingest. Use carefully near mucous membranes.
Side effects of Zema Cream
Most patients tolerate Zema Cream (Econazole Nitrate) well. Possible side effects include:
Common (1–10%): Burning, itching, or irritation at the application site, particularly at the start of treatment
Uncommon: Skin dryness, peeling, redness
Very rare: Allergic contact dermatitis — swelling, hives
If severe allergic reactions occur (e.g., spreading rash, unusual swelling, difficulty breathing), discontinue use and seek medical attention immediately. Consult a pharmacist if you have sensitive skin.
Contraindications / Precautions
Contraindications:
Known allergy to Econazole, other Imidazoles, or any ingredient in the cream
Do not apply directly to the eyes
Precautions:
Pregnancy: Consult a doctor or pharmacist before use, especially in the first trimester
Breastfeeding: Avoid applying to areas that may come into contact with the infant
Children under 2 years: Use only under medical supervision
Zema Cream is for external use only — do not swallow
Wash hands after each application to prevent spreading infection to other areas
Zema Cream vs other antifungal creams
There are several topical antifungal cream options; each differs in active ingredient and spectrum of activity:
Canesten Cream (Clotrimazole 1%) — Also an Imidazole; effective against ringworm, Candida, and pityriasis versicolor; slightly higher priced than Zema
Nizoral Cream (Ketoconazole 2%) — Higher concentration; especially effective for pityriasis versicolor and Candida; higher priced, 15 g tube
Tonaf (Tolnaftate 1%) — Active only against dermatophytes (ringworm, athlete's foot); does not cover Candida; very affordable
Summary: Zema Cream (Econazole) is best for those wanting a broad-spectrum antifungal covering ringworm, pityriasis versicolor, and Candida at an affordable price. Canesten is comparable but slightly pricier; Nizoral focuses on versicolor/Candida at higher cost; Tonaf is cheapest but lacks Candida coverage.
How fast does Zema Cream work?
Econazole Nitrate begins its antifungal action within hours of the first application, though visible clinical improvement depends on infection type and severity:
Ringworm / Jock itch: Itching reduces within 3–5 days; rash clears within 2–4 weeks
Pityriasis versicolor: Abnormal skin colour diminishes within 2–4 weeks; even skin tone may take several months to return
Athlete's foot: Peeling and itch reduce within 1–2 weeks; complete the 4-week course to prevent recurrence
⚠️ Important: Complete the full treatment course even if symptoms appear to resolve — residual fungal spores can cause recurrence if treatment is stopped early. Consult a pharmacist if no improvement within 2 weeks.
Where to buy Zema Cream?
Where to buy Zema Cream?
Order Zema Cream online at Intimo Life with delivery across Thailand within 1–3 business days. All orders are discreetly packaged with no product name on the outer parcel.
⚠️ Disclaimer
The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.
Itching typically reduces within 3–5 days, but the full course of 2–4 weeks must be completed to eliminate all fungal cells. Stopping early allows residual spores to cause a relapse.
Fungal skin infections are caused by groups of fungi: dermatophytes (ringworm), Malassezia (pityriasis versicolor), and Candida (moist skin folds). Risk factors include high humidity, excessive sweating, weakened immunity, and contact with infected people or public areas such as bathrooms and swimming pools.
Yes. Zema Cream (Econazole Nitrate 1%) directly inhibits Malassezia furfur, the organism causing pityriasis versicolor. Apply once to twice daily for 2–4 weeks. Note that skin discolouration may take several months to return to normal even after the infection is cleared.
With caution and pharmacist guidance. Econazole can generally be applied to facial skin when a true fungal infection is present (e.g., facial ringworm), but avoid areas around the eyes and mucous membranes, and apply the minimum effective amount.
A mild burning or itching sensation is possible when first applying, especially on inflamed or cracked skin. This is usually temporary and subsides within a few days of regular use. If burning is severe or the rash spreads, stop using and consult a pharmacist.
While topical antifungals have no direct dietary restrictions, reducing high-sugar foods and refined carbohydrates may support faster recovery. Stay well hydrated, wear breathable clothing, and keep the affected area clean and dry.
Both contain Econazole Nitrate as the active ingredient. The difference is formulation: Zema Cream has a thicker consistency, better for dry skin or areas needing moisture; Zema Lotion is lighter and dries faster, suitable for large body areas or the scalp. Efficacy is comparable.
Yes. Jock itch (Tinea cruris) is caused by dermatophytes, which Econazole in Zema Cream directly targets. Apply a thin layer to the groin area and surroundings twice daily for 2–4 weeks. Wearing breathable underwear and changing daily will help accelerate recovery.
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