Travogen Cream (Isoconazole Nitrate 1%) — broad-spectrum antifungal cream with antibacterial activity against Gram-positive bacteria. Treats ringworm, tinea cruris, athlete's foot, pityriasis versicolor, and mixed fungal-bacterial skin infections.
💊 Active: Isoconazole Nitrate 1% — broad-spectrum antifungal with Gram-positive antibacterial action
⏱️ Use: Apply to clean skin 2-3 times daily for 2-4 weeks continuously
🍽️ Conditions: Apply to clean, dry skin only. Avoid contact with eyes, mouth, nose
📦 Pack: 10 g cream tube, manufactured by Bayer AG, Germany
⚡ Highlight: Isoconazole's dual antifungal + antibacterial action makes it ideal for mixed infections
🌡️ Storage: Below 30°C, away from direct sunlight, do not freeze
Antifungal skin treatment Travogen Cream (Isoconazole Nitrate 1%) is an imidazole antifungal that inhibits ergosterol synthesis in fungal cell membranes, leading to cell wall disruption and fungal death. Uniquely among topical antifungals, Isoconazole also exhibits antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus — which commonly co-infects fungal skin conditions — making Travogen especially suitable when mixed infection is suspected.
📊 Key statistics:
Tinea infections (ringworm/tinea corporis, tinea cruris, tinea pedis) affect 20-25% of the global population, with higher prevalence in tropical climates like Thailand (WHO, 2023)
Gram-positive bacterial co-infection occurs in 30-40% of patients presenting with fungal skin complaints (Journal of Dermatology, 2022)
Isoconazole provides broad coverage against Candida, Trichophyton, Microsporum and Epidermophyton species (StatPearls, 2024)
Travogen Cream is manufactured by Bayer AG, Germany — a global pharmaceutical leader with international GMP certification
🏭 Manufactured by Bayer AG, Germany. Thai FDA Registration No. 1A 84/56
⚠️ Avoid contact with eyes. Do not ingest. Consult a pharmacist if allergic reactions occur or symptoms do not improve within 2 weeks.
Medically reviewed by
ทีมเนื้อหา Intimo Life | Sources: StatPearls, NHS, WHO, Drugs.com, MIMS
Last reviewed: 2026-06-04
About Travogen Cream
What is Travogen Cream?
Travogen Cream (Isoconazole Nitrate 1%) is a broad-spectrum antifungal skin treatment manufactured by Bayer AG, Germany. It belongs to the imidazole antifungal class and works by inhibiting the cytochrome P450 14α-demethylase enzyme in fungal cells, blocking ergosterol synthesis and causing cell wall disruption.
Isoconazole uniquely also demonstrates antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus species. This makes Travogen especially suited for mixed fungal-bacterial skin infections common in hot and humid climates.
Travogen Cream is registered with Thailand's Food and Drug Administration under registration number 1A 84/56. For external use only.
What does Travogen Cream treat?
Travogen Cream (antifungal cream, Isoconazole) is indicated for a broad range of fungal skin infections:
Ringworm (Tinea corporis) — itchy expanding rings on body, arms and legs
Jock itch (Tinea cruris) — fungal infection of the groin and skin folds
Athlete's foot (Tinea pedis) — fungal infection of the soles and between toes
Pityriasis versicolor — white or brown skin discoloration patches
Cutaneous candidiasis — Candida yeast infection on skin and folds
Mixed fungal-bacterial infection — a key advantage of Isoconazole over other antifungals
Travogen is effective against Trichophyton rubrum, T. mentagrophytes, Microsporum canis, Epidermophyton floccosum, Candida albicans and most pathogenic skin fungi.
How to use Travogen Cream / Dosage
How to apply Travogen antifungal cream for best results:
Cleanse: Wash the affected area with mild soap and pat completely dry before applying
Amount: Apply a thin layer covering the rash and extending 1-2 cm around the border
Frequency: 2-3 times daily (morning/evening or morning/noon/evening)
Duration: Continue for 2-4 weeks. Do not stop early even if symptoms improve
Tonaf (Tolnaftate) — Affordable thiocarbamate; does not cover Candida, no antibacterial activity
Zema Cream (Econazole) — Broad-spectrum imidazole; no antibacterial activity
In summary: Choose Travogen (Isoconazole) when bacterial co-infection is suspected (significant redness, pus or tenderness). Choose Canesten or Nizoral for straightforward fungal infections without signs of bacterial involvement.
Can Travogen Cream be used with other medications?
Travogen Cream has minimal systemic absorption, so drug interactions with oral medications are rare. Key points:
Topical corticosteroids: Do not apply to the same area without medical advice
Other topical antifungals: Combination not needed as Travogen already has broad coverage
Oral antibiotics: May be used concurrently if prescribed; consult your pharmacist
Moisturizers/lotions: Apply Travogen first, wait 10-15 minutes, then apply other products
Always inform your pharmacist about all medications and products you use before starting Travogen Cream.
How fast does Travogen Cream work?
Expected timeline after starting Travogen antifungal cream:
Days 2-3: Itching and irritation may begin to subside as Isoconazole starts inhibiting fungal growth
1-2 weeks: Redness and rash size should visibly reduce
2-4 weeks: Full resolution in most cases — complete the full course even if symptoms improve early
⚠️ Stopping treatment early is the main cause of recurrence. Complete the full dosing period and consult a pharmacist if there is no improvement after 2 weeks.
Where to buy Travogen Cream?
Where to buy Travogen Cream?
Order Travogen Cream online at Intimo Life with nationwide delivery in Thailand within 1-3 business days. Discreet packaging — product name not shown on the parcel.
Travogen Cream (Isoconazole Nitrate 1%) treats ringworm, jock itch, athlete's foot, pityriasis versicolor, and cutaneous candidiasis. It is effective against Trichophyton, Microsporum, Epidermophyton and Candida albicans, and uniquely also has antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus.
Treatment duration is typically 2-4 weeks depending on infection type: ringworm/jock itch 2-4 weeks / athlete's foot 3-4 weeks / pityriasis versicolor 2-3 weeks. Itching may start improving within 2-3 days, but complete the full course to prevent recurrence.
Both are imidazole antifungals but Travogen uses Isoconazole which has additional Gram-positive antibacterial activity — ideal when bacterial co-infection is suspected. Canesten uses Clotrimazole, which is purely antifungal, suitable for straightforward tinea without signs of bacterial involvement.
Yes. Travogen Cream directly treats tinea cruris (jock itch) in the groin. Apply a thin layer 2-3 times daily. Always clean and dry the area before applying, especially in skin folds where moisture accumulates.
During fungal treatment, reduce sugar, sweets, white bread and alcohol as sugar promotes fungal growth. Increase probiotic foods like yogurt and maintain clean, dry skin to support recovery.
Children aged 2 years and above may use it under pharmacist or doctor guidance. For children under 2 years, consult a pediatrician first as thinner skin means higher absorption.
If the infection shows significant redness, pus or tenderness, bacterial co-infection may be present. Travogen Cream (Isoconazole) is most appropriate as it acts against both fungi and Gram-positive bacteria. For severe cases, consult a pharmacist or doctor.
Mild burning in the first 2-3 days is normal. If burning is severe, the rash spreads, or symptoms don't improve within 5-7 days, stop use and consult a pharmacist — you may be experiencing an allergic reaction.
Yes. Fungal skin infections spread through direct contact with an infected person or animal, and through sharing personal items such as towels, clothing and shoes. Wash hands after applying medication and wash clothing in hot water during treatment.
Check the current price of Travogen Cream 10 g on the product page at Intimo Life. Order online with nationwide delivery across Thailand.
Related Products
Products with the same active ingredient or treating the similar condition.
Canesten Cream Antifungal Clotrimazole 1% 10g
