Antifungal Lotion Zema Lotion contains Econazole Nitrate 1%, an imidazole antifungal agent that inhibits ergosterol synthesis in fungal cell membranes, causing cell death and stopping spread. The light lotion texture absorbs quickly into skin, ideal for hairy or wide areas such as the scalp, chest and trunk where cream absorbs less effectively.
📊 Statistical Data
Dermatophytosis affects approximately 10-15% of the Thai population, especially in hot and humid climates
Econazole Nitrate has over 90% efficacy against Trichophyton, Microsporum, Candida and Pityrosporum per NCBI StatPearls
Continuous treatment for 2-4 weeks reduces fungal skin infection recurrence by up to 85%
🏭 Manufacturer: Unison Laboratories Ltd. | Drug Registration No. 1A 70/41 ⚠️ Consult a pharmacist before use if pregnant or have underlying conditions
Medically reviewed by
ทีมเนื้อหา Intimo Life | แหล่งข้อมูล: NCBI, NHS, Drugs.com, Mayo, MIMS
Last reviewed: 2026-06-04
About Zema Lotion
What is Zema Lotion?
Zema Lotion is a topical antifungal in lotion form containing Econazole Nitrate 1%, an Azole antifungal that inhibits the enzyme 14α-demethylase in ergosterol synthesis — a vital component of fungal cell membranes. This disrupts membrane integrity, halting fungal growth and causing cell death.
Zema Lotion is effective against multiple fungal species including Dermatophytes (ringworm, jock itch, athlete's foot), Candida, and Pityrosporum ovale (cause of tinea versicolor). Its light lotion formulation is particularly suited for hairy or wide-area applications where cream is harder to apply.
Pityriasis versicolor (tinea versicolor) — white or brown patches on trunk from Pityrosporum ovale
Cutaneous candidiasis — Candida infection on skin folds
Zema Lotion is especially suited for hairy areas such as the scalp, chest and back, as the lotion formulation penetrates hair follicles more effectively than cream.
How to apply Zema Lotion / Dosage
How to apply Zema Lotion:
Clean the affected area with soap and water
Dry thoroughly before applying — moisture promotes fungal growth
Squeeze Zema Lotion onto a finger or cotton and apply a thin layer over the affected area
Cover the lesion and extend 1-2 cm beyond the border
Apply 1-2 times daily (morning and evening) or as directed by a pharmacist
Important: continue applying even after symptoms improve to prevent recurrence
Side effects of Zema Lotion
Zema Lotion is generally well tolerated. Possible side effects include:
Common: Mild burning, stinging or irritation at the application site, especially initially
Occasional: Redness, itching or dry peeling skin at the application area
Rare: Allergic reactions such as urticaria, swelling or difficulty breathing
If you experience severe irritation, allergic reaction, or worsening symptoms after 2 weeks of use, stop and consult a pharmacist or doctor immediately.
Contraindications / Precautions
Do not use if you have a known allergy to Econazole or other Azole antifungals
Avoid contact with eyes, mouth or mucous membranes; if contact occurs, rinse thoroughly with water
Do not apply to open wounds or severely inflamed skin
Pregnancy and breastfeeding: consult a pharmacist or doctor before use
Children under 2 years: not recommended without medical supervision
For external use only — do not ingest
Zema Lotion vs Other Topical Antifungals
Topical antifungal options in our store differ in formulation, active ingredient and indication:
Zema Cream (Econazole Nitrate 1%) — Same active ingredient in cream form; ideal for small, localized lesions on smooth skin without hair
Simple guide: Choose Zema Lotion for wide areas or hairy zones like scalp, chest and trunk | Choose Zema Cream for small lesions on smooth skin | Choose Canesten or Nizoral to switch active ingredient or when infection persists
How fast does Zema Lotion work?
After applying Zema Lotion, expected timeline:
Days 2-4: Itching and burning begin to subside
Week 1-2: Lesions start to fade, skin begins to recover
Canesten Cream is a topical antifungal cream containing Clotrimazole 1% by Bayer. It treats ringworm, tinea versicolor (pityriasis versicolor), athlete's foot, jock itch, and other superficial fungal skin infections. For external use only.
No. Canesten Cream (1% topical) is designed for external skin use only. It is different from Canesten vaginal pessaries/suppositories used for vaginal thrush, which have different concentrations and formulations. Do not substitute one for the other.
Fungal skin infections are caused by dermatophytes that thrive in warm, moist environments. Risk factors include prolonged damp clothing, shared towels, weakened immunity, and contact with infected surfaces. Prevention involves keeping skin dry, regular bathing, and not sharing personal items.
Treat skin fungal infections with topical Clotrimazole such as Canesten Cream, applied 2–3 times daily for 2–4 weeks depending on the type and location. Continue for 1 additional week after symptoms clear to eliminate residual spores.
No. Canesten Cream contains only Clotrimazole 1% with no added steroids. This differs from Myda-B which combines Clotrimazole with Betamethasone (a corticosteroid). The absence of steroids makes Canesten Cream safer for longer-term use and for sensitive skin.
Mild burning or itching during the first few days is normal, especially on inflamed skin. It usually resolves within 2–3 days. If burning is severe or hives develop, discontinue use and consult a doctor or pharmacist.
There are no strict dietary restrictions when using Canesten Cream topically, as systemic absorption is minimal. However, keeping skin dry and well-ventilated, wearing breathable clothing, and avoiding excessive sweating will support faster recovery.
Canesten Cream can be used on children over 2 years old under medical or pharmacist guidance. For children under 2 years, consult a doctor before use. Apply a thin layer only to the affected area; avoid the face and area around the eyes.
Ringworm/jock itch: 2–4 weeks | Athlete's foot: 3–4 weeks | Tinea versicolor: 2–3 weeks. Apply 2–3 times daily consistently. Do not stop early even if symptoms improve, as residual fungal spores may cause recurrence.
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