Bestatin — A statin medication that helps lower bad cholesterol (LDL) and prevent cardiovascular disease.
💊 Active Ingredient — Simvastatin
⏰ Take once daily — In the evening or before bed, with or without food
📦 Package — 1 box contains 10 strips (10 tablets per strip, 100 tablets total)
✅ Key Benefit — Long-established medication with proven safety data at an affordable price
🏭 Manufacturer — Berlin Pharmaceutical
🌡️ Storage — Store below 30°C, protect from light and moisture
Bestatin is a cholesterol-lowering medication in the HMG-CoA reductase inhibitor class, commonly known as "statins." Its active ingredient is Simvastatin, which works by inhibiting the enzyme responsible for cholesterol production in the liver. This results in lower levels of bad cholesterol (LDL-C) in the blood and helps reduce the risk of cardiovascular disease.
This medication is suitable for people with high cholesterol levels or those who need to prevent coronary heart disease and stroke, especially high-risk individuals such as diabetic patients or those with a history of vascular disease.
To order Bestatin, customers must register with Intimo Life and consult with our pharmacist first to ensure the medication is appropriate for their health condition and that there are no contraindications.
About Zimva
What is Bestatin?
Bestatin is a cholesterol-lowering medication containing Simvastatin as its active ingredient. It belongs to the HMG-CoA reductase inhibitor class, commonly known as "statins." It is manufactured by Berlin Pharmaceutical Industry Co., Ltd., a leading pharmaceutical company in Thailand.
This medication is used to treat hyperlipidemia (high cholesterol), particularly to reduce LDL-C (bad cholesterol) levels, and to prevent cardiovascular disease in high-risk patients.
How Does Bestatin Work?
Simvastatin in Bestatin works by inhibiting the HMG-CoA reductase enzyme, which is essential for cholesterol production in the liver. When this enzyme is inhibited:
Cholesterol production in the liver decreases
The body responds by increasing LDL receptors on liver cell surfaces
This allows more bad cholesterol (LDL-C) to be removed from the bloodstream
Resulting in lower blood cholesterol levels and reduced cardiovascular risk
The drug is rapidly absorbed and metabolized in the liver via the CYP3A4 enzyme, then excreted through bile and feces.
How to Take Bestatin
For Adults and Children Over 17 Years
Starting dose: 10-20 mg once daily in the evening or before bed
Usual dose: 20-40 mg once daily
Maximum dose: 80 mg per day (reserved only for patients who have been on this dose for more than 12 months without muscle problems; not recommended for new patients)
Can be taken with or without food
Should be taken at the same time every day
For Children Aged 10-17 Years (Heterozygous Familial Hypercholesterolemia)
Starting dose: 10 mg once daily in the evening
Recommended dose: 10-40 mg per day (as determined by the physician)
For Patients with Kidney Disease or Elderly Patients
Dose reduction may be necessary, especially in patients with severe kidney impairment (CrCl < 30 mL/min)
Consult a doctor or pharmacist before use
If You Miss a Dose
Take it as soon as you remember
If it's almost time for your next dose, skip the missed dose
Never take a double dose
Side Effects of Bestatin
Common Side Effects
Headache, dizziness, insomnia
Constipation, bloating, nausea
Mild muscle pain
Symptoms Requiring Immediate Medical Attention
Severe unexplained muscle pain or weakness
Dark-colored urine (cola-colored) — may indicate rhabdomyolysis
Yellowing of skin or eyes (jaundice) — may indicate liver problems
Warnings and Precautions
Contraindications
Allergy to Simvastatin or other statins
Active liver disease or severe liver impairment
Pregnancy and breastfeeding — absolutely contraindicated
Things to Avoid
Grapefruit juice: Avoid large amounts as it inhibits the enzyme that breaks down the drug, increasing blood levels and risk of severe side effects
Alcohol: Limit consumption as it increases risk of liver abnormalities
Regular blood tests are recommended to monitor cholesterol levels and liver function
Do not stop the medication without consulting your doctor
Medication should be combined with diet control and regular exercise
Where to Buy Bestatin?
You can order Bestatin online at Intimo Life. Customers must register and consult with our pharmacist first to ensure the medication is appropriate for their health condition and that there are no contraindications. After approval, you can place orders directly through our website.
Frequently Asked Questions About Bestatin
Why should Bestatin be taken in the evening or before bed?
Because the body produces the most cholesterol at night. Taking the medication during this time maximizes its effectiveness in inhibiting cholesterol production.
How long do I need to take Bestatin?
Cholesterol-lowering medications are typically taken continuously for the long term, possibly for life, to keep cholesterol levels at target and prevent complications.
How is Bestatin different from Atorvastatin?
Simvastatin (Bestatin) is an older statin with long-established safety data and a more affordable price. Atorvastatin is a newer statin that may be more effective at lowering LDL at equivalent doses.
Do I need to control my diet while taking this medication?
Absolutely. Medication is only part of the treatment. Controlling your diet by reducing fatty and fried foods, along with regular exercise, is essential for the best treatment results.
Can Bestatin cause diabetes?
There is data suggesting that statin use may slightly increase the risk of developing diabetes, especially in those with existing risk factors. However, the benefits of the medication in preventing cardiovascular disease significantly outweigh this risk.
Why is the 80 mg dose particularly risky?
The 80 mg dose carries a significantly higher risk of causing rhabdomyolysis (muscle breakdown), which is a serious condition. Its use is restricted to patients who have been on this dose for a long time without problems, and it should not be started in new patients.
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