Preme Contraceptive Pill

Preme

115.00 ฿
(฿4.11/tablet)
Shipping calculated at checkout.

Preme — A gentle combined hormonal contraceptive designed for women who want reliable protection while taking care of their skin and body shape.

💧 Reduces Water Retention — The gentle formula helps minimize bloating, keeping you feeling light and comfortable throughout the month.
Skin Care Benefits — Helps reduce facial oiliness and certain types of acne, promoting a smoother and clearer complexion.
📅 Available in 21 and 28-Day Packs — Choose the format that fits your lifestyle, whether you prefer a pill-free break or a continuous daily routine.
💊 Reliable Contraception — Provides high-efficiency pregnancy prevention when taken consistently and correctly according to instructions.
⚖️ Ideal for Long-Term Use — Its mild formulation allows many users to continue their regimen comfortably with minimal side effects.
💸 Affordable Quality — An excellent value choice for those who prioritize both effective birth control and overall self-care.

Variant: 28 Pills
Shipping

Discreet shipping within Thailand — packaging does not identify the product. Customers can review shipping and return conditions per our store policy. Contact our team for any questions.

Variant

Product Description

Oral contraceptives are one of the most popular and highly effective methods of family planning. Preme is a Combined Oral Contraceptive (COC) containing Desogestrel 150 mcg + Ethinyl Estradiol 30 mcg — the same formulation as Marvelon, but as a Thai generic brand at a more accessible price.

📊 Key Facts

  • Combined oral contraceptives are up to 99% effective when taken consistently
  • Desogestrel is a third-generation progestin with low androgenic side effects
  • Preme is manufactured by Berlin Pharmaceutical, a GMP-certified Thai company
  • See other contraceptives in the Contraceptive collection

🏭 Preme is manufactured by Berlin Pharmaceutical, a Thai pharmaceutical company. Same formulation as Marvelon (originator by Organon) but as a Thai generic at a more affordable price. Thai FDA approved.

⚠️ Oral contraceptives must be taken consistently at the same time every day for maximum pregnancy prevention effectiveness.

Supatcheree A., Pharmacist

Medically reviewed by

Supatcheree A., Pharmacist | Sources: NHS, StatPearls, Drugs.com

Last reviewed: 2026-02-17

About Preme

What is Preme?

Preme is a Combined Oral Contraceptive (COC) containing Desogestrel 150 mcg + Ethinyl Estradiol (EE) 30 mcg as its active ingredients. It is manufactured by Berlin Pharmaceutical in Thailand.

Combined oral contraceptives work by suppressing ovulation, thickening cervical mucus to prevent sperm from reaching the egg, and thinning the uterine lining to reduce the chance of embryo implantation.

Preme has the same formulation as Marvelon (the originator brand by Organon). The only differences are the brand name and a more accessible price — it is a Thai generic at an affordable cost.

What is Preme used for?

Contraception: Preme is used for pregnancy prevention. When taken correctly and consistently, it is up to 99% effective.

Additional benefits:

  • Regulates menstrual cycles
  • Reduces menstrual pain
  • Decreases menstrual blood flow
  • May help reduce acne in some users

Does not protect against: Sexually transmitted infections (STIs) — condoms should be used alongside for STI prevention.

How to Take Preme / Dosage

Dosage: Take 1 tablet daily at the same time each day. Each pack contains 21 tablets.

How to take: Take for 21 consecutive days → stop for 7 days (withdrawal bleeding will occur) → start a new pack on day 8.

Starting for the first time:

  • Start the first tablet on day 1 of your period — protection is immediate
  • If starting on another day, use additional protection (condoms) for the first 7 days

If you miss a pill:

  • Less than 12 hours late — take it as soon as you remember; protection is maintained
  • More than 12 hours late — take it as soon as you remember and use additional protection for 7 days

Side Effects of Preme

Common side effects:

  • Nausea (usually resolves after 2–3 months)
  • Headache
  • Breast tenderness
  • Mood changes
  • Breakthrough bleeding (spotting)

Rare but serious side effects:

  • Blood clots (DVT/PE) — slightly increased risk, especially in smokers
  • High blood pressure
  • Severe migraine

When to stop and seek medical help:

  • Severe leg pain or swelling, chest pain, difficulty breathing
  • Unusually severe headache
  • Sudden blurred vision

Contraindications & Precautions

Do not use:

  • History of blood clots (DVT, PE, stroke)
  • Cardiovascular disease
  • Smokers over 35 years old
  • Migraine with aura
  • Pregnant or suspected pregnancy
  • Breast cancer
  • Severe liver disease

Use with caution:

  • High blood pressure
  • Overweight (BMI > 35)
  • Family history of blood clots
  • Breastfeeding (consider progestin-only alternatives)

How Does Preme Compare to Other Contraceptives?

Preme vs. Marvelon: Same active ingredients — Desogestrel 150 mcg + EE 30 mcg. Marvelon is the originator brand by Organon at a higher price. Preme is a Thai generic by Berlin Pharmaceutical at a more affordable price. Equivalent efficacy.

Preme vs. Mercilon: Mercilon contains only 20 mcg EE (low-dose) compared to Preme's 30 mcg EE. Mercilon may suit those wanting lower estrogen to reduce side effects but may have more spotting initially.

Preme vs. Yasmin: Yasmin uses Drospirenone instead of Desogestrel, offering anti-androgenic (acne reduction) and anti-mineralocorticoid (reduces water retention) properties. Better for acne or bloating but at a higher price.

Preme vs. Cerazette: Cerazette is a progestin-only pill (Desogestrel 75 mcg) without estrogen. Suitable for those who cannot use estrogen, such as breastfeeding women or those with COC contraindications.

How Quickly Does Preme Work?

If you start Preme on the first day of your period, it provides immediate pregnancy protection. If starting on any other day, use additional protection (such as condoms) for 7 days.

Important to know:

  • The pill is most effective when taken at the same time every day
  • Missing pills, vomiting, or severe diarrhoea may reduce effectiveness
  • Some medications may reduce the pill's effectiveness, such as certain antibiotics and anticonvulsants
  • Fertility returns to normal within 1–3 months after stopping

Where Can I Buy Preme?

Preme is a pharmacist-dispensed medication. You can order online from Intimo Life.

Can I buy Preme online?

Yes. Order through Intimo Life — select the product, consult with a licensed pharmacist online, and receive your medication at home.

Do I need a prescription?

A doctor's prescription is not required, but the medication must be dispensed by a licensed pharmacist. At Intimo Life, our pharmacist will review your symptoms and health history to confirm suitability before shipping.

How does Intimo Life ship orders?

We deliver nationwide in Thailand with discreet packaging — no product names on the outside.

⚠️ Disclaimer

The information on this page is for general informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment from a qualified doctor or pharmacist. If you have any questions about your symptoms or medication, always consult a doctor or pharmacist first.

Frequently Asked Questions

Both contain the same active ingredients — Desogestrel 150 mcg + EE 30 mcg. Marvelon is the originator brand by Organon at a higher price. Preme is a Thai generic by Berlin Pharmaceutical at an accessible price. Both have equivalent efficacy.

If less than 12 hours late, take it as soon as you remember — protection is maintained. If more than 12 hours late, take it immediately and use additional protection such as condoms for 7 days.

Combined oral contraceptives may cause slight weight gain in some users, mostly due to water retention rather than fat. This usually resolves after 2–3 months of adjustment. If concerned, Yasmin with its anti-mineralocorticoid properties may help reduce water retention.

During the 7-day break, withdrawal bleeding normally occurs. Occasionally missing a period can be normal, but if you miss two consecutive periods, take a pregnancy test and consult your doctor.

Not recommended. Preme contains estrogen which may reduce breast milk supply. Breastfeeding women should choose a progestin-only pill like Cerazette, which is estrogen-free and safe during breastfeeding.

Yes. After stopping Preme, fertility returns to normal within 1–3 months. Some women may conceive as early as the first month after stopping. There is no need to wait.

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