Lynestrenol
Exluton — a lynestrenol progestin-only pill, an alternative when estrogen cannot be used
💊 Active ingredient: Lynestrenol
⏱️ How to use: 1 tablet daily, same time, no more than 3 hours off schedule
🍽️ Conditions: With or without food
📦 Pack: 28 tablets per strip, every tablet active
⚡ Highlight: Taken continuously with no break, even during your period
🌡️ Storage: Below 30°C, away from sun and moisture
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What is Exluton?
Exluton is a progestin-only pill with lynestrenol and no estrogen, suiting breastfeeding mothers, estrogen-intolerant users, or those at high clot risk who cannot use combined pills. It works mainly by thickening cervical mucus to block sperm. Take one tablet daily with no break at all — every one of the 28 tablets in the strip is an active hormone tablet.
🛒 28 tablets per strip · authentic · 24-hour dispatch from Intimo Life — consult a pharmacist or doctor before use.
Product Description
Lynestrenol in Exluton is a different progestin from Cerazette (desogestrel) and Slinda (drospirenone), also sold at Intimo Life. All three are progestin-only pills with no estrogen, but lynestrenol is an older-generation progestin that works mainly by thickening cervical mucus to block sperm, rather than reliably suppressing ovulation the way the other two do. This is why Exluton requires stricter daily timing, and every tablet in the strip is an active hormone tablet with no placebo days like a 24+4 formula.
📊 Comparison data
- Missed-dose tolerance window: Exluton 3 hours, versus Cerazette 12 hours and Slinda 24 hours
- Worldwide, about 874 million women use a modern contraceptive method out of 1.9 billion women of reproductive age
🏭 Manufactured by N.V. Organon in the Netherlands and listed under the WHO Prequalification Programme for reproductive health, sold only as a 28-tablet strip as registered
⚠️ Anyone who frequently runs more than 3 hours late should ask a pharmacist about a progestin-only pill with a longer tolerance window
About Exluton
What is Exluton?
Exluton is a progestin-only pill (POP) with lynestrenol as its sole active ingredient and no estrogen. Lynestrenol is an older-generation progestin, converted by the body into norethisterone, that works mainly by thickening cervical mucus so sperm cannot reach the egg, plus thinning the uterine lining against implantation. This differs from newer POPs like desogestrel or drospirenone, which suppress ovulation more consistently. Exluton relies mainly on the mucus effect, so it must be taken at the same time every day to keep that effect steady. Each strip has 28 active hormone tablets, with no placebo days like a combined pill or a 24+4 formula.
Who is Exluton suitable for?
Exluton suits women who cannot use an estrogen-containing pill — breastfeeding mothers (estrogen can reduce milk supply), those with migraine with aura, smokers over 35, anyone with a clot history or uncontrolled high blood pressure, or anyone estrogen-intolerant. Since it has no estrogen, it does not raise clot risk the way combined pills do. It also suits anyone who wants a simple daily pill with no hormone-free days to count. However, Exluton is not an acne or hirsutism treatment like Diane-35, since it has no anti-androgen effect, so it does not suit someone whose main goal is a skin or hair benefit.
How to take Exluton / Dosage
Exluton comes only in a 28-tablet strip — take one tablet daily at the same time, continuously with no break, even during your period. Finish a strip and start the next one the very next day with no gap, unlike combined pills with a 7-day break. Crucially, Exluton must be taken within the same time window, no more than 3 hours late, since its mucus-based effect needs steady hormone levels — unlike Cerazette, which allows 12 hours. Starting on day one of the cycle gives immediate protection; any other day needs backup contraception, such as condoms, for 2 days. Switching from another pill, start Exluton the day right after finishing the previous pack.
Side effects of Exluton
The most common side effect of a progestin-only pill like Exluton is spotting or irregular bleeding in the first few months. Some also get headache, breast tenderness, mood changes, mild acne or oilier skin (lynestrenol has slightly more androgenic activity than newer progestins), or reduced libido. Most of these ease within 2-3 months as the body adjusts. Important: if pregnancy occurs on a progestin-only pill, there is a slightly higher relative chance it is ectopic — seek medical care immediately for severe lower abdominal pain with a suspected pregnancy.
Contraindications / Precautions for Exluton
Do not use with current breast cancer, unexplained vaginal bleeding, severe liver disease, or pregnancy. Certain anticonvulsants, rifampicin-type antibiotics, and St. John’s Wort speed up liver hormone breakdown and can cut Exluton’s effect — tell your pharmacist about any other medicine and use backup contraception while taking one. Since Exluton needs strict 3-hour timing, anyone with an irregular schedule or who often forgets doses should ask about a more forgiving option first. Stop and see a doctor immediately for severe lower abdominal pain or suspected pregnancy.
Exluton compared with other progestin-only pills
Exluton uses the older progestin lynestrenol, relying mainly on cervical mucus, so it needs strict 3-hour dosing. This differs from Cerazette (desogestrel), which suppresses ovulation more consistently with up to 12 hours of flexibility — both come in a 28-tablet, all-hormone strip. Slinda (drospirenone) instead uses 24 hormone tablets plus 4 placebo, giving a scheduled bleed like a combined pill and up to 24 hours of flexibility. In short: choose Exluton for a budget-friendly option if strict timing isn’t a concern, Cerazette for more flexibility, and Slinda for a predictable monthly bleed.
Can Exluton be taken with other medicines?
Certain medicines clearly reduce Exluton's effect: liver-enzyme-inducing anticonvulsants like carbamazepine and phenytoin, rifampicin-type antibiotics for tuberculosis, and St. John's Wort mood supplements. These speed up liver hormone breakdown, making lynestrenol levels too low. Use backup contraception, such as condoms, during and for 28 days after stopping an interacting medicine. Ordinary antibiotics like amoxicillin do not meaningfully reduce Exluton's effect. Always tell your pharmacist about any new medicine or herbal supplement.
How fast does Exluton work?
Starting the first tablet on day one of the cycle gives immediate protection. Starting on any other day needs backup contraception, such as condoms, for 2 days, since cervical mucus thickens quickly — unlike combined pills, which usually need a full 7 days. This is because Exluton relies mainly on cervical mucus, which responds faster than ovulation suppression. But protection only holds with same-time daily dosing — a dose missed or taken over 3 hours late lets the mucus thin again within hours, restarting the 2-day backup requirement.
Where to buy Exluton?
Where to buy Exluton?
Order online at Intimo Life with nationwide Thailand delivery in 1-3 business days. Packed discreetly for privacy, with no product name shown on the parcel box.
⚠️ ข้อจำกัดความรับผิดชอบ
เนื้อหาในบทความนี้มีจุดประสงค์เพื่อให้ความรู้ทั่วไปเท่านั้น ไม่ได้มีเจตนาทดแทนคำแนะนำ การวินิจฉัย หรือการรักษาจากแพทย์หรือเภสัชกรผู้เชี่ยวชาญ หากมีข้อสงสัยเกี่ยวกับอาการหรือการใช้ยา ควรปรึกษาแพทย์หรือเภสัชกรก่อนเสมอ
References
- NHS UK. Progestogen-only pill (POP). NHS. 2026.
- World Health Organization. Family planning/contraception. WHO. 2024.
- Cooper DB, Adigun R. Oral Contraceptive Pills. StatPearls. NCBI Bookshelf. 2024.
- Britton LE, et al. Progestins. StatPearls. NCBI Bookshelf. 2023.
- WHO Prequalification Team. Public Assessment Report: Exluton/Exlutena (lynestrenol) 0.5mg tablets. WHO. 2019.
Frequently Asked Questions
Take the missed tablet as soon as you remember, then continue at the usual time. Since over 3 hours have passed, cervical mucus may have thinned, reducing protection — use backup contraception, such as condoms, for 2 days. If you had sex in the 2-3 days before, ask a pharmacist about emergency contraception too.
This is normal, since every tablet in Exluton is active with no placebo break like combined pills have. Some people may see no bleeding at all throughout use, while others may have irregular spotting instead — both patterns are normal for a progestin-only pill. If you're worried about pregnancy, take a pregnancy test for peace of mind.
No. Exluton does not have the anti-androgen effect that cyproterone in Diane-35 has. Lynestrenol actually has mild androgenic activity, so some users may notice oilier skin or slight acne instead of improvement. Anyone specifically wanting a pill to help with hormonal acne should choose a formula with anti-androgen activity instead.
Most research finds no significant weight gain from progestin-only pills. Any weight change some users notice is usually linked to appetite or temporary mild water retention rather than direct fat gain, and typically settles down as the body adjusts within the first few months.
It's best to start the first tablet on day one of your menstrual cycle (the first day of your period) so contraceptive protection begins immediately. Starting on any other day of the cycle requires backup contraception for the next 2 days.
After stopping, it can take 1-3 months for cycles to become regular again as hormones rebalance following long-term continuous dosing with no placebo break. If your period doesn't return within 3 months of stopping, consult a doctor to check for other causes.
Yes, taking it earlier causes no harm — what matters is taking it every day at roughly the same time. Just avoid taking it less than 24 hours after the previous tablet to prevent accidentally doubling up, and make the new time your regular time going forward.
Not necessarily, if condoms are used correctly every time. However, combining both methods adds confidence in preventing pregnancy, especially if Exluton doses are often taken off schedule, and adds protection against sexually transmitted infections, which condoms guard against but the pill does not.
If you've taken Exluton on schedule, no extra emergency pill is needed since protection is still active. But if a recent dose was over 3 hours late, ask a pharmacist about emergency contraception and watch your next period.
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