
Itraconazole
Spornar
Spornar — oral Itraconazole antifungal capsules for tinea and nail fungus that topical treatment hasn't cured
💊 Itraconazole
⏱️ Take once daily for the course your pharmacist advises
🍽️ Take right with a main meal for better absorption
📦 Pack of 4 capsules/strip
⚡ Broad-spectrum action covering both tinea and nail fungus
🌡️ Store below 30°C, away from sunlight and moisture
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What is Itraconazole?
Itraconazole is an oral triazole antifungal with broad-spectrum activity against many fungi. It treats widespread tinea infections and stubborn nail fungus unresponsive to topical treatment. Unlike topical antifungals, it is absorbed into the bloodstream and accumulates in nail keratin, reaching fungus deep within the nail. Use only as directed by a pharmacist or doctor.
🛒 Pack of 4 capsules/strip · authentic · 24-hour dispatch from Intimo Life — consult a doctor or pharmacist before use.
Product Description
Oral antifungal medicine Spornar contains Itraconazole, a broad-spectrum triazole antifungal effective against many fungal species. It suits widespread tinea infections or fingernail/toenail fungus that has not responded to topical treatment. Unlike typical topical antifungals, Itraconazole is absorbed into the bloodstream and accumulates in nail keratin, reaching fungus hidden deep within the nail.
📊 Key facts about Itraconazole
- It is a potent CYP3A4 enzyme inhibitor, so it can interact with many other medicines taken together
- Pulse therapy (3 cycles) for toenail fungus shows a clinical cure rate of about 58% at 12-month follow-up
- Temporary elevated liver enzymes occur in about 1-5% of users, usually asymptomatic and self-resolving
- The drug persists in nail tissue for months after stopping, so it keeps working even after the course ends
🏭 Spornar is manufactured by CBLAB and registered as a modern medicine in Thailand
⚠️ Do not use in patients with heart failure or a history of heart failure, and always tell your pharmacist before combining with other medicines due to high interaction risk
About Itraconazole
What is Itraconazole?
Itraconazole is a triazole antifungal, the active ingredient in Spornar. It works by blocking the enzyme fungi use to make ergosterol, an essential component of the fungal cell membrane. As the membrane weakens, the fungus can no longer grow and is eventually eliminated.
Itraconazole's strength is its broad spectrum, covering both true dermatophytes and certain yeasts — unlike topical antifungals that only act on the outer skin layer. Spornar comes as 100 mg capsules, packed 4 capsules per strip, intended for a course as advised by a pharmacist.
What does Itraconazole treat?
Itraconazole treats several types of skin and nail fungal infections, especially when topical treatment has not worked:
- Tinea corporis/cruris (ringworm) — widespread itchy red rings on the body or groin
- Pityriasis versicolor — scattered white or brown patches that topical creams can't fully reach
- Onychomycosis (nail and toenail fungus) — thickened, discolored, brittle nails where topical treatment can't penetrate deep enough, requiring an oral antifungal instead
- Fungal infections in skin folds — recurring or spreading itchy rash around the groin area
It suits people with widespread infection, frequent recurrence, or infections that haven't improved with continuous topical treatment. Itraconazole covers both tinea and nail fungus more broadly than topical antifungals, especially when the rash has spread widely across the body or fungal skin-fold infections keep recurring.
How to take Itraconazole and dosage
Take Spornar (Itraconazole 100 mg) right with a full meal to help the body absorb the medicine better. Swallow the capsule whole with a full glass of water — do not chew or crush it.
Dose and duration depend on the type of fungal infection and your pharmacist's or doctor's judgment. Tinea infections typically need a short course of 1-2 weeks, while nail fungus usually requires several weeks to months of continuous use, or pulse therapy taken in cycles as directed.
Important: Do not stop the medicine early even if symptoms improve, as the fungus may not be fully eliminated yet and can return.
Side effects of Itraconazole
Common, usually mild side effects:
- Nausea, vomiting, bloating, stomach pain
- Headache
- Mild skin rash or slight itching
⚠️ Serious side effects requiring immediate discontinuation and medical attention: yellowing of the eyes or skin, dark urine, unusual tiredness, or severe upper abdominal pain (signs of liver problems), as well as difficulty breathing, leg or foot swelling, or rapid unexplained weight gain (signs the heart is working harder than normal)
If a spreading rash, fever, or mouth blistering occurs, stop the medicine and see a doctor immediately as well.
Contraindications / Precautions
Do not use Itraconazole in these cases:
- Heart failure or a history of heart failure — the drug can reduce heart muscle contraction and may worsen symptoms
- Severe liver disease or abnormal liver function — increases the risk of liver toxicity
- Taking medicines with serious interactions with Itraconazole, such as certain statins or heart rhythm medicines — always consult a pharmacist first
Extra caution is needed in pregnancy, as animal studies show potential risk to the fetus. Always consult a doctor before use if you have an existing condition or are pregnant.
Oral vs Topical Antifungals — Which Should You Choose?
Not every skin fungal infection needs an oral medicine — choose based on severity:
- Itraconazole (oral) — suits widespread or recurring infections, or nail fungus that topical treatment can't reach
- Nizoral Cream (Ketoconazole) — topical treatment for small, localized tinea patches
- Canesten Cream (Clotrimazole) — general topical antifungal, easy to use for localized areas
- Zema Cream (Econazole) — topical treatment for mild skin fungus and fungal infections in skin folds
In short: choose a topical cream for mild, localized infections, and choose Itraconazole for widespread infections or nail fungus unresponsive to topical treatment, on a pharmacist's advice.
Can Itraconazole be taken with other medicines?
Itraconazole is a potent CYP3A4 enzyme inhibitor, so it interacts with several classes of medicine that need special caution:
- Certain statin cholesterol medicines (e.g. simvastatin, lovastatin) — blood levels may rise enough to risk muscle breakdown
- Certain heart rhythm medicines — may increase the risk of serious irregular heartbeat
- Stomach acid reducers (antacids, PPIs, H2 blockers) — reduce Itraconazole absorption since it needs an acidic stomach environment; doses should be spaced apart
Always tell your pharmacist or doctor what medicines you are taking before starting Itraconazole, for safety.
How fast does Itraconazole work?
For skin tinea infections, the rash usually starts fading within the first 1-2 weeks of treatment, but the full course should still be completed as directed by a pharmacist to fully clear the fungus.
For nail fungus, results take much longer since the infected nail must grow out completely and be replaced by healthy new nail — this can take several months even after finishing the course, as the drug keeps working from what's stored in the nail tissue.
Where to buy Itraconazole?
Where to buy Itraconazole?
Order Spornar (Itraconazole) online at Intimo Life with nationwide delivery across Thailand in 1-3 business days, packed discreetly with no product name shown on the parcel.
⚠️ Disclaimer
The content in this article is for general educational purposes only. It is not intended to replace professional advice, diagnosis, or treatment from a doctor or pharmacist. If you have any questions about symptoms or medication use, always consult a doctor or pharmacist first.
References
- NHS Specialist Pharmacy Service. Itraconazole. NHS SPS. 2024.
- Mayo Clinic. Itraconazole (oral route). Mayo Clinic. 2024.
- DermNet NZ. Itraconazole. DermNet NZ. 2023.
- StatPearls. Itraconazole. NCBI Bookshelf. 2024.
- PubMed. Itraconazole pulse therapy for onychomycosis and dermatomycoses: an overview. 1997.
Frequently Asked Questions
Take it as soon as you remember on the same day. If it's almost time for your next dose, skip the missed one and continue as usual. Never double up to make up for a missed dose, as this unnecessarily raises the risk of side effects.
It can be used in certain cases under a specialist doctor's judgment, such as severe or treatment-resistant fungal infection. It is not a medicine to give children on your own for general symptoms — it always requires a doctor's supervision.
It's best to limit or avoid alcohol while on this medicine, since both alcohol and Itraconazole put extra strain on the liver. Drinking during treatment can raise the risk of liver inflammation or abnormal liver enzymes.
Yes, it can recur, especially if the course isn't completed or if you're still exposed to the same fungal source, such as unwashed shoes or socks. Complete the full course as advised and keep up good hygiene alongside treatment to reduce the chance of recurrence.
For longer courses, a doctor or pharmacist may recommend periodic liver function tests, especially for people with existing liver conditions or those taking other liver-affecting medicines, to monitor safety during treatment.
No, it doesn't work against every type of fungus. Itraconazole has broad activity against many dermatophytes and yeasts, but some fungi may be resistant or require a different antifungal. A pharmacist or doctor should confirm the type of infection before choosing treatment.
It generally does not cause drowsiness or directly affect concentration, so normal activities like driving are fine. However, if you feel dizzy or unwell after taking it, pay attention to how you feel before doing tasks that require high concentration.
Store below 30°C in a dry place, away from direct sunlight and humidity. Close the cap tightly after each use and keep out of reach of children.
Always take the medicine with a meal to reduce stomach irritation. Mild diarrhea usually improves as the body adjusts, but if it's severe or continues for several days, tell your pharmacist or doctor for evaluation.
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