Viagra

Viagra is the original ED medication manufactured by Pfizer, USA. It received FDA approval on March 27, 1998, making it the first PDE5 Inhibitor approved for treating erectile dysfunction (ED).

The active ingredient is Sildenafil Citrate, formulated as the iconic blue diamond-shaped film-coated tablet recognized worldwide.

Viagra isn't just for those with ED problems — it's also suitable for men who want extra confidence and assurance whenever they need it.

Viagra works by inhibiting Phosphodiesterase Type 5 (PDE5), an enzyme that breaks down cGMP (cyclic guanosine monophosphate) in blood vessels.

Mechanism of Action:

1. When sexually aroused, the body releases Nitric Oxide (NO)
2. NO stimulates cGMP production, which relaxes smooth muscle in blood vessels
3. Relaxed blood vessels allow increased blood flow to the penis
4. Viagra inhibits PDE5 from breaking down cGMP, allowing cGMP to persist longer
5. The result is a fuller, longer-lasting erection

Important: Viagra requires sexual stimulation to work. It will not cause an automatic erection.

For Adults

1. Take 1 tablet approximately 30-60 minutes before sexual activity
2. Can be taken anywhere from 30 minutes to 4 hours before activity
3. Do not take more than 1 tablet per day
4. Can be taken with or without food
5. Avoid high-fat meals as they may delay the medication's effect
6. Effects last approximately 4-6 hours

Dose Adjustment:

• Your doctor or pharmacist may adjust the dose based on effectiveness and tolerance
• If the medication isn't working or causes side effects, consult your doctor

For Elderly (65 years and older)

• Starting with a lower dose is recommended
• Blood levels may be higher than normal

For Patients with Underlying Conditions

Severe kidney impairment (CLcr < 30 mL/min):

• Starting with a lower dose is recommended

Liver impairment:

• Starting with a lower dose is recommended

Those taking certain medications:

• If taking Alpha-blockers: Start with a lower dose
• If taking CYP3A4 inhibitors (e.g., Ritonavir, Ketoconazole): Dose reduction required

Common side effects (≥2%):

• Headache
• Flushing (feeling of warmth)
• Dyspepsia (indigestion)
• Nasal congestion
• Back pain, muscle pain
• Nausea
• Dizziness
• Changes in color vision (blue/green tinge)

Symptoms requiring immediate medical attention:

• Erection lasting more than 4 hours (Priapism) — requires immediate treatment to prevent permanent damage
• Sudden vision loss
• Sudden hearing loss, ringing in ears
• Chest pain, severe dizziness, fainting

Viagra can be ordered online at Intimo Life. Customers must register and consult with our pharmacist first to ensure this medication is safe and appropriate for you.

Since Viagra has many contraindications and drug interactions, especially with Nitrates, pharmacist consultation before use is essential.

Do not use if you:

• Take Nitrates (heart medications) such as Nitroglycerin, Isosorbide — may cause severe life-threatening drop in blood pressure
• Take Guanylate Cyclase Stimulators such as Riociguat
• Are allergic to Sildenafil or other ingredients
• Have severe heart conditions where sexual activity is not advised

Use with caution if you have:

• Heart disease, high or low blood pressure
• History of stroke
• Anatomical deformation of the penis
• Blood disorders such as Sickle Cell Anemia
• History of vision loss from NAION

Medications requiring caution:

• Alpha-blockers (blood pressure medications)
• Other antihypertensive medications
• Antifungals such as Ketoconazole, Itraconazole
• Antibiotics such as Erythromycin
• Antivirals such as Ritonavir

Avoid:

• Excessive alcohol — may increase side effects and reduce effectiveness
• Grapefruit juice — may increase drug levels in blood

What's the difference between Viagra and generic Sildenafil?

Viagra is the brand name for Sildenafil manufactured by Pfizer, the original developer. Generic Sildenafil is produced by other companies after the patent expired. Both contain the same active ingredient, but Viagra is the recognized brand with Pfizer's manufacturing standards.

How long does Viagra last?

Viagra begins working within 30-60 minutes after taking it, and its effects last approximately 4-6 hours.

Does Viagra cause automatic erection?

No. Viagra requires sexual stimulation to work. It helps achieve better erection when aroused but doesn't cause automatic erection.

Can I take Viagra with alcohol?

Avoid excessive alcohol while using Viagra as it may increase side effects like dizziness and reduce the medication's effectiveness.

Is Viagra addictive?

No. Viagra doesn't cause physical addiction. However, some may feel psychological dependence. Consult your doctor if you have concerns.

Why can't Viagra be used with Nitrates?

Both Viagra and Nitrates dilate blood vessels. When used together, they can cause severe, life-threatening drop in blood pressure.

• MedlinePlus — Sildenafil
• Pfizer — Viagra Prescribing Information
• NCBI — Sildenafil StatPearls
• DrugBank — Sildenafil